p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis (Q28141296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10611223%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis (English)

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2 November 2019

0 references

0 references

1

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2 November 2019

Hong-Gang Wang

5

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2 November 2019

author name string

A F Mooney

2

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2 November 2019

L C Sanders

3

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2 November 2019

M A Sells

4

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2 November 2019

J C Reed

6

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2 November 2019

G M Bokoch

7

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2 November 2019

language of work or name

English

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publication date

1 January 2000

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Molecular and Cellular Biology

2 November 2019

published in

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2 November 2019

volume

20

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2 November 2019

issue

2

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2 November 2019

page(s)

453-461

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Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

2 November 2019

cites work

1 reference

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Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

20 March 2017

1 reference

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

20 March 2017

1 reference

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

20 March 2017

1 reference

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

20 March 2017

1 reference

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The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

20 March 2017

1 reference

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

20 March 2017

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

20 March 2017

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

20 March 2017

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The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

20 March 2017

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Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

20 March 2017

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Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

20 March 2017

1 reference

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Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

20 March 2017

1 reference

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Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

20 March 2017

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

20 March 2017

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Mitochondria and apoptosis

20 March 2017

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

7 April 2017

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Activation of Rac and Cdc42 by integrins mediates cell spreading

7 April 2017

1 reference

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Programmed cell death in animal development

7 April 2017

1 reference

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

7 April 2017

1 reference

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Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

7 April 2017

1 reference

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Emerging from the Pak: the p21-activated protein kinase family.

7 April 2017

1 reference

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Monoglucosylation of low-molecular-mass GTP-binding Rho proteins by clostridial cytotoxins

29 September 2017

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Suppression of Ras-induced apoptosis by the Rac GTPase

29 September 2017

1 reference

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Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

29 September 2017

1 reference

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Anti-apoptotic function of Rac in hematopoietic cells.

29 September 2017

1 reference

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Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

29 September 2017

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Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant

29 September 2017

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A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

29 September 2017

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Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

29 September 2017

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Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

29 September 2017

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A member of the Ste20/PAK family of protein kinases is involved in both arrest of Xenopus oocytes at G2/prophase of the first meiotic cell cycle and in prevention of apoptosis

29 September 2017

1 reference

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Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells

29 September 2017

1 reference

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Temporal phases in apoptosis defined by the actions of Src homology 2 domains, ceramide, Bcl-2, interleukin-1beta converting enzyme family proteases, and a dense membrane fraction

29 September 2017

1 reference

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

29 September 2017

1 reference

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Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors

29 September 2017

1 reference

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Intracellular signaling pathways activated by neurotrophic factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Preparation and characterization of an endogenously fluorescent annexin for detection of apoptotic cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

PI3K: downstream AKTion blocks apoptosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21-activated kinases

2 June 2018

1 reference

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

2 June 2018

1 reference

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Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

High‐level Expression of the Human Neurokinin‐1 Receptor in Mammalian Cell Lines using the Semliki Forest Virus Expression System

2 June 2018

1 reference

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2 June 2018

Bcl-2 family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Apoptosis CED-4 is a stranger no more

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85099

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

27 November 2018

1 reference

12 December 2020

Controlling cell death

1 reference

12 December 2020

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

12 December 2020

Checkpoints of dueling dimers foil death wishes

1 reference

12 December 2020

Apoptosis meets signal transduction: elimination of a BAD influence

1 reference

12 December 2020

p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells

1 reference

12 December 2020

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

1 reference

12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

12 December 2020

10.1128/MCB.20.2.453-461.2000

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10611223%20AND%20SRC:MED&resulttype=core&format=json

release_eup45xs2kbf5dghseayj3owsaq

2 November 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eup45xs2kbf5dghseayj3owsaq

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10611223%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

10611223

2 references