Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2 (Q28143997)

2

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D Perdereau

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J Girard

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A F Burnol

Cloning and characterization of GRB14, a novel member of the GRB7 gene family

5

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language of work or name

English

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publication date

13 April 2000

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published in

Oncogene

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volume

19

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issue

16

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page(s)

2052-9

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cites work

1 reference

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Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma

21 January 2018

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Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

21 January 2018

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Signalling by receptor tyrosine kinases

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Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

21 January 2018

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Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains

21 January 2018

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Improved method for high efficiency transformation of intact yeast cells

21 January 2018

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Association of focal adhesion kinase with Grb7 and its role in cell migration

21 January 2018

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Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus

21 January 2018

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Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

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Identification of the rat adapter Grb14 as an inhibitor of insulin actions

21 January 2018

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The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts

21 January 2018

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Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function

21 January 2018

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Grb10/GrbIR as an in vivo substrate of Tec tyrosine kinase

21 January 2018

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The GRB family of SH2 domain proteins

21 January 2018

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High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains

21 January 2018

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The role of mGrb10alpha in insulin-like growth factor I-mediated growth

21 January 2018

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Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins

21 January 2018

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Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

21 January 2018

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Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling

21 January 2018

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The Ret Receptor Protein Tyrosine Kinase Associates with the SH2-containing Adapter Protein Grb10

21 January 2018

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Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7

21 January 2018

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Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

21 January 2018

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A novel variant of human Grb7 is associated with invasive esophageal carcinoma

21 January 2018

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Signal transduction by receptors with tyrosine kinase activity

21 January 2018

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Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

21 January 2018

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Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

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The Grb7 Family of Signalling Proteins

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Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10

21 January 2018

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Evidence for a direct interaction between insulin receptor substrate-1 and Shc

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An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

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Expression of Grb7 growth factor receptor signaling protein in kidney development and in adult kidney

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The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action

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7 January 2021