Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase (Q28180283)

ceramide catabolic process

GOA release 2020-03-11

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GOA release 2020-03-11

8

Edward H Schuchman

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author name string

Xingxuan He

1

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Nozomu Okino

2

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Rajwinder Dhami

3

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Arie Dagan

4

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Shimon Gatt

5

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Heike Schulze

6

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Konrad Sandhoff

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

29 August 2003

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published in

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volume

278

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issue

35

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page(s)

32978-86

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cites work

The role of ceramide in cell signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Purification, characterization, and biosynthesis of human acid ceramidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Human acid ceramidase: processing, glycosylation, and lysosomal targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

The human acid ceramidase gene (ASAH): structure, chromosomal location, mutation analysis, and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Molecular analysis of acid ceramidase deficiency in patients with Farber disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Synthesis of fluorescent substrates and their application to study of sphingolipid metabolism in vitro and in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Overexpression of human alpha-galactosidase A results in its intracellular aggregation, crystallization in lysosomes, and selective secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Characterization of human acid sphingomyelinase purified from the media of overexpressing Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

A fluorescence-based high-performance liquid chromatographic assay to determine acid ceramidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Molecular Cloning of the Acid Sphingomyelinase of the Mouse and the Organization and Complete Nucleotide Sequence of the Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Analysis of the lung pathology and alveolar macrophage function in the acid sphingomyelinase--deficient mouse model of Niemann-Pick disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Interfacial regulation of acid ceramidase activity. Stimulation of ceramide degradation by lysosomal lipids and sphingolipid activator proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Purification and characterization of a novel ceramidase from Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Characterization of the acid β-d-galactosidases from human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Identification and characterization of the molecular lesion causing mucopolysaccharidosis type I in cats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Purification and characterization of recombinant human lysosomal alpha-mannosidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Correction of glycogen storage disease type II by enzyme replacement with a recombinant human acid maltase produced by over-expression in a CHO-DHFR(neg) cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Purification and characterization of recombinant human alpha-N-acetylglucosaminidase secreted by Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Enzymes of ceramide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

[14C]ceramide synthesis by sphingolipid ceramide N-deacylase: new assay for ceramidase activity detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Reverse hydrolysis reaction of a recombinant alkaline ceramidase of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

Hormonal effects on the activities of glycosidases in the endometrium of rabbit uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

The urine from patients with peritonitis as a rich source for purifying human acid sphingomyelinase and other lysosomal enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301936200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301936200

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Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12815059

1 reference

Consolidated OpenCitations Corpus – April 2017