Ribosome structure and the mechanism of translation (Q28209121)

Structural studies of the translational apparatus

Europe PubMed Central

title

Ribosome structure and the mechanism of translation (English)

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author

Venkatraman Ramakrishnan

object named as

V Ramakrishnan

series ordinal

1

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language of work or name

English

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publication date

22 February 2002

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published in

Cell

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volume

108

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issue

4

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page(s)

557-72

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Effect of buffer conditions on the position of tRNA on the 70 S ribosome as visualized by cryoelectron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Template-free ribosomal synthesis of polylysine from lysyl-tRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Truncated elongation factor G lacking the G domain promotes translocation of the 3' end but not of the anticodon domain of peptidyl-tRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Translocation in Protein Synthesis: A Hybrid Structure Model

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Crystal structure of an initiation factor bound to the 30S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Codon--anticodon pairing: the wobble hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Protection patterns of tRNAs do not change during ribosomal translocation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Interaction of translation initiation factor 3 with the 30S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

STREPTOMYCIN, SUPPRESSION, AND THE CODE

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A universal mode of helix packing in RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Identification of molecular interactions between P-site tRNA and the ribosome essential for translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A ratchet-like inter-subunit reorganization of the ribosome during translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Solution structure of the ribosome-binding domain of E. coli translation initiation factor IF3. Homology with the U1A protein of the eukaryotic spliceosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Factor-free ("non-enzymic") and factor-dependent systems of translation of polyuridylic acid by Escherichia coli ribosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Ribosomes and translation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Initiation of mRNA translation in prokaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

High resolution structure of the large ribosomal subunit from a mesophilic eubacterium

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Domains of initiator tRNA and initiation codon crucial for initiator tRNA selection by Escherichia coli IF3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Neurobiology: internal model visualized.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Ribosome recycling by ribosome recycling factor (RRF)--an important but overlooked step of protein biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

EF-G-catalyzed translocation of anticodon stem-loop analogs of transfer RNA in the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Novel roles for classical factors at the interface between translation termination and initiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Characterization of functionally active subribosomal particles from Thermus aquaticus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Translational termination comes of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Initiation factor IF 2 binds to the alpha-sarcin loop and helix 89 of Escherichia coli 23S ribosomal RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Location of translational initiation factor IF3 on the small ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Intermediate states in the movement of transfer RNA in the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The allosteric three-site model for the ribosomal elongation cycle: features and future

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Kinetic amplification of enzyme discrimination

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The structural basis of ribosome activity in peptide bond synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

RNA tertiary interactions in the large ribosomal subunit: the A-minor motif

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Unusual resistance of peptidyl transferase to protein extraction procedures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Recognition of cognate transfer RNA by the 30S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Conformationally Restricted Elongation Factor G Retains GTPase Activity but Is Inactive in Translocation on the Ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Translation initiation factor IF3: two domains, five functions, one mechanism?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A stereospecific mechanism for the aminoacyl-tRNA selection at the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Selective perturbation of G530 of 16 S rRNA by translational miscoding agents and a streptomycin-dependence mutation in protein S12.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Atomic structures at last: the ribosome in 2000.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Visualization of elongation factor Tu on the Escherichia coli ribosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Late events of translation initiation in bacteria: a kinetic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Unveiling ribosomal structures: the final phases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Conformational change of elongation factor Tu (EF-Tu) induced by antibiotic binding. Crystal structure of the complex between EF-Tu.GDP and aurodox

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

An inhibitor of ribosomal peptidyl transferase using transition-state analogy

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probing

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Functional sites of interaction between release factor RF1 and the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Structure of the 30S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Transit of tRNA through the Escherichia coli ribosome. Cross-linking of the 3' end of tRNA to specific nucleotides of the 23 S ribosomal RNA at the A, P, and E sites

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Recognition of the codon-anticodon helix by ribosomal RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Crystal structure of the ribosome at 5.5 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

The path of messenger RNA through the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

A posttermination ribosomal complex is the guanine nucleotide exchange factor for peptide release factor RF3.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

Binding of Escherichia coli protein synthesis initiation factor IF1 to 30S ribosomal subunits measured by fluorescence polarization.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900619-0

7 January 2021

10.1016/S0092-8674(02)00619-0

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11909526

1 reference

Consolidated OpenCitations Corpus – April 2017