Direct identification of PTEN phosphorylation sites (Q28203697)

2

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David C Seldin

3

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William S Lane

4

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Benjamin G Neel

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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language of work or name

English

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publication date

25 September 2002

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published in

FEBS Letters

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volume

528

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issue

1-3

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page(s)

145-53

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

The multiple roles of PTEN in tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Mutations of the human PTEN gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

PTEN: life as a tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Allelic imbalance, including deletion of PTEN/MMACI, at the Cowden disease locus on 10q22-23, in hamartomas from patients with Cowden syndrome and germline PTEN mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Pten is essential for embryonic development and tumour suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Protein tyrosine phosphatases: mechanisms of catalysis and regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

PTEN and myotubularin: novel phosphoinositide phosphatases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Phosphorylation of the PTEN tail regulates protein stability and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Casein kinase II is a selective target of HIV-1 transcriptional inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Emodin, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum, selectively inhibits the activity of casein kinase II as a competitive inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

New models of lymphoma in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Protein kinase CK2 in mammary gland tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X

Infrequent mutations in the PTEN/MMAC1 gene among primary breast cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903274-X