Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme (Q28216644)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464614%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme (English)

1 reference

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15 December 2019

1 reference

3

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15 December 2019

Kumar Sambamurti

4

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15 December 2019

author name string

Elizabeth A Eckman

1

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15 December 2019

Mona Watson

2

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15 December 2019

Christopher B Eckman

5

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15 December 2019

language of work or name

English

0 references

publication date

2 December 2002

1 reference

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Journal of Biological Chemistry

15 December 2019

published in

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15 December 2019

volume

278

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15 December 2019

issue

4

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15 December 2019

page(s)

2081-2084

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Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

15 December 2019

cites work

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

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Metabolic regulation of brain Abeta by neprilysin

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Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains

21 January 2018

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Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures.

21 January 2018

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Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen.

21 January 2018

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Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity

21 January 2018

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Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation

21 January 2018

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Degradation of amyloid beta-protein by a serine protease-alpha2-macroglobulin complex

21 January 2018

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Clearing the brain's amyloid cobwebs

21 January 2018

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Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

21 January 2018

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Molecular pharmacology of endothelin converting enzymes

21 January 2018

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ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

21 January 2018

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21 January 2018

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Cellular distribution of endothelin-converting enzyme-1 in human tissues.

21 January 2018

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Endothelin converting enzyme-1-, endothelin-1-, and endothelin-3-like immunoreactivity in the rat brain

21 January 2018

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Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum

21 January 2018

1 reference

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Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

21 January 2018

1 reference

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

21 January 2018

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

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Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased Abeta42 secretion.

21 January 2018

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FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction

21 January 2018

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Accumulation of murine amyloidbeta42 in a gene-dosage-dependent manner in PS1 'knock-in' mice.

21 January 2018

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

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Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization

21 January 2018

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The gene defects responsible for familial Alzheimer's disease

21 January 2018

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The endothelin system and its potential as a therapeutic target in cardiovascular disease.

21 January 2018

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Endothelin-converting enzyme inhibitors: current status and perspectives.

21 January 2018

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Synthesis of triazole-Tethered pyrrolidine libraries: novel ECE inhibitors

21 January 2018

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Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin

21 January 2018

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Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin

21 January 2018

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A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C200642200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464614%20AND%20SRC:MED&resulttype=core&format=json

release_xwo6m2ixsbdq5fe52sqezg5ug4

15 December 2019

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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2 references

Consolidated OpenCitations Corpus – April 2017