Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours (Q28253060)

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J Lee

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P Robins

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P Heller

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A Ruiz i Altaba

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

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language of work or name

English

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publication date

23 October 1997

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published in

Nature

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volume

389

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issue

6653

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page(s)

876-81

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cites work

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Human homolog of patched, a candidate gene for the basal cell nevus syndrome

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The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

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Basal cell carcinomas in mice overexpressing sonic hedgehog

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Identification of an amplified, highly expressed gene in a human glioma

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GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

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gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development

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Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

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The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A

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Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos

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Progressive determination during formation of the anteroposterior axis in Xenopus laevis.

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Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development

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Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice

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Proliferating cells of human basal cell carcinoma are located on the periphery of tumor nodules

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Early Stages of Notochord and Floor Plate Development in the Chick Embryo Defined by Normal and Induced Expression of HNF-3β

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Catching a Gli-mpse of Hedgehog

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The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

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Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly

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Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

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Sonic hedgehog is expressed in epithelial cells during development of whisker, hair, and tooth.

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HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

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Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin

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A search for gli expression in tumors of the central nervous system

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A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

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