Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin (Q28269309)

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David Kuninger

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Mahta Nili

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Peter Rotwein

American Journal of Physiology - Cell Physiology

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language of work or name

English

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publication date

April 2008

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published in

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volume

294

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issue

4

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page(s)

C994-C1003

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https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Hemochromatosis: genetics and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Netrins: beyond the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Role of RGM coreceptors in bone morphogenetic protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

RGMa inhibition promotes axonal growth and recovery after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Balancing acts: molecular control of mammalian iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

A mouse model of juvenile hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Complex biosynthesis of the muscle-enriched iron regulator RGMc

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

RGM and its receptor neogenin regulate neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

RGM is a repulsive guidance molecule for retinal axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Insulin-like growth factor (IGF) binding protein-5 blocks skeletal muscle differentiation by inhibiting IGF actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Eph receptor signalling casts a wide net on cell behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Current concepts in RET-related genetics, signaling and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Apoptosis initiated by dependence receptors: a new paradigm for cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Neogenin mediates the action of repulsive guidance molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Netrin signaling leading to directed growth cone steering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

DRAGON, a bone morphogenetic protein co-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Isolation and expression pattern of three mouse homologues of chick Rgm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

From developmental disorder to heritable cancer: it's all in the BMP/TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Netrins promote developmental and therapeutic angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Control of MyoD function during initiation of muscle differentiation by an autocrine signaling pathway activated by insulin-like growth factor-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00563.2007