The FoxO code (Q28275268)

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English	The FoxO code	scientific article

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Europe PubMed Central

The FoxO code (English)

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D R Calnan

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A Brunet

2

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7 April 2008

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27

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16

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2276-88

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FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Effects of aging and caloric restriction on the gene expression of Foxo1, 3, and 4 (FKHR, FKHRL1, and AFX) in the rat skeletal muscles

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR.

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Mammalian SIRT1 represses forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding

1 reference

https://api.crossref.org/works/10.1038/ONC.2008.21

21 April 2017

Extended longevity in mice lacking the insulin receptor in adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

FoxO3 controls autophagy in skeletal muscle in vivo

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

21 April 2017

Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Regulation of the Forkhead Transcription Factor FKHR (FOXO1a) by Glucose Starvation and AICAR, an Activator of AMP-Activated Protein Kinase

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Shear stress-induced activation of the AMP-activated protein kinase regulates FoxO1a and angiopoietin-2 in endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Long-lived Drosophila with overexpressed dFOXO in adult fat body

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

A FoxO-Smad synexpression group in human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Chromatin opening and stable perturbation of core histone:DNA contacts by FoxO1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

DAF-16 target genes that control C. elegans life-span and metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

The 14-3-3 protein FTT-2 regulates DAF-16 in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

The forkhead transcription factor Foxo1 regulates adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

E2F-1 regulates expression of FOXO1 and FOXO3a

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Characterization of Insulin Inhibition of Transactivation by a C-terminal Fragment of the Forkhead Transcription Factor Foxo1 in Rat Hepatoma Cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

An integrated mass spectrometric and computational framework for the analysis of protein interaction networks.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Drosophila Melted modulates FOXO and TOR activity.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Insulin Inhibition of Transcription Stimulated by the Forkhead Protein Foxo1 Is Not Solely due to Nuclear Exclusion

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

SMK-1, an essential regulator of DAF-16-mediated longevity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

From worm to human: bioinformatics approaches to identify FOXO target genes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.21

31 March 2020

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