Splicing of a rare class of introns by the U12-dependent spliceosome (Q28275293)

Europe PubMed Central

title

Splicing of a rare class of introns by the U12-dependent spliceosome (English)

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main subject

spliceosome

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U12-type prespliceosome

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U12-type catalytic step 1 spliceosome

GO:0071015

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U4atac/U6atac x U5 tri-snRNP complex

GO:0071017

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U12-type catalytic step 2 spliceosome

GO:0071009

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U12-type precatalytic spliceosome

GO:0071018

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U12-type post-mRNA release spliceosomal complex

GO:0071016

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Mechanisms of alternative pre-messenger RNA splicing

GO:0071019

author

Reinhard Georg Lührmann

series ordinal

2

object named as

Reinhard Lührmann

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Cindy L Will

series ordinal

1

object named as

Cindy L Will

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language of work or name

English

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publication date

August 2005

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published in

Biological Chemistry

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volume

386

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issue

8

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page(s)

713-24

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cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Evolutionary fates and origins of U12-type introns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The question remains: is the spliceosome a ribozyme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Terminal intron dinucleotide sequences do not distinguish between U2- and U12-dependent introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Role of the 3' splice site in U12-dependent intron splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Modified nucleotides at the 5' end of human U2 snRNA are required for spliceosomal E-complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Initial recognition of U12-dependent introns requires both U11/5' splice-site and U12/branchpoint interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Molecular Architecture of the Multiprotein Splicing Factor SF3b

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Major Conformational Change in the Complex SF3b upon Integration into the Spliceosomal U11/U12 di-snRNP as Revealed by Electron Cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Alternative splicing: increasing diversity in the proteomic world

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Base pairing with U6atac snRNA is required for 5' splice site activation of U12-dependent introns in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A reappraisal of non-consensus mRNA splice sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Pre-mRNA splicing: awash in a sea of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

OrCGDB: a database of genes involved in oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The human Prp8 protein is a component of both U2- and U12-dependent spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The evolution of spliceosomal introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

SR proteins and splicing control

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A revised model for U4atac/U6atac snRNA base pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Splicing double: insights from the second spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The splicing of U12-type introns can be a rate-limiting step in gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Large-scale proteomic analysis of the human spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Initial splice-site recognition and pairing during pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

An intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The intramolecular stem-loop structure of U6 snRNA can functionally replace the U6atac snRNA stem-loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A catalytically active group II intron domain 5 can function in the U12-dependent spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

U4 small nuclear RNA can function in both the major and minor spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Characterization of the catalytic activity of U2 and U6 snRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Spliceosomal UsnRNP biogenesis, structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Identification of both shared and distinct proteins in the major and minor spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

U1-mediated exon definition interactions between AT-AC and GT-AG introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Purine-rich enhancers function in the AT-AC pre-mRNA splicing pathway and do so independently of intact U1 snRNP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Site-specific crosslinking of mammalian U11 and u6atac to the 5' splice site of an AT-AC intron

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Comprehensive proteomic analysis of the human spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

U2–U6 RNA folding reveals a group II intron-like domain and a four-helix junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Metal ion catalysis during splicing of premessenger RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

Diffusion mechanisms in metallic supercooled liquids and glasses

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2005.084

21 January 2018

Identifiers

DOI

10.1515/BC.2005.084

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16201866

1 reference

Consolidated OpenCitations Corpus – April 2017