Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases (Q28271592)

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English	Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases	scientific article

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Europe PubMed Central

title

Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases (English)

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2

Gregg L Semenza

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author name string

Kiichi Hirota

series ordinal

1

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language of work or name

English

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publication date

9 December 2005

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published in

Biochemical and Biophysical Research Communications

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volume

338

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issue

1

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page(s)

610-6

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cites work

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/20459

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Siah: new players in the cellular response to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Oxygen signal transduction

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

The inhibitory effect of sodium nitroprusside on HIF-1 activation is not dependent on nitric oxide-soluble guanylyl cyclase pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBRC.2005.08.193

Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eucaryotes

1 reference

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

12 October 2022

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Role of nitric oxide in the regulation of HIF-1alpha expression during hypoxia

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

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A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

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Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau

1 reference

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

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Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

1 reference

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Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

1 reference

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

1 reference

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Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

1 reference

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Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells

1 reference

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

1 reference

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Hypoxia-inducible factor 1, a master transcription factor of cellular hypoxic gene expression.

1 reference

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

1 reference

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1 reference

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HIF-1 and tumor progression: pathophysiology and therapeutics

1 reference

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Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

1 reference

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Purification and characterization of hypoxia-inducible factor 1

1 reference

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1 reference

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10.1016/J.BBRC.2005.08.193

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PubMed publication ID

16154531

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7607360

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Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases (Q28271592)

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Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases (Q28271592)

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