Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human alpha1C subunit gene (Q28272430)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9607315%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human alpha1C subunit gene (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9607315%20AND%20SRC:MED&resulttype=core&format=json

alternative mRNA splicing, via spliceosome

12 November 2019

main subject

1 reference

2

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12 November 2019

author name string

R D Zühlke

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9607315%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

N M Soldatov

series ordinal

3

1 reference

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12 November 2019

H Reuter

series ordinal

4

1 reference

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12 November 2019

language of work or name

English

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publication date

1 May 1998

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12 November 2019

1 reference

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12 November 2019

volume

427

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12 November 2019

issue

2

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12 November 2019

page(s)

220-224

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Functional subunit structure of voltage-gated calcium channels

12 November 2019

cites work

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Molecular basis for Ca2+ channel diversity

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Structure and regulation of L-type calcium channels a current assessment of the properties and roles of channel subunits

21 January 2018

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Molecular localization of regions in the L-type calcium channel critical for dihydropyridine action

21 January 2018

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Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity

21 January 2018

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Motif III S5 of L-type calcium channels is involved in the dihydropyridine binding site. A combined radioligand binding and electrophysiological study

21 January 2018

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Analysis of the Dihydropyridine Receptor Site ofl-type Calcium Channels by Alanine-scanning Mutagenesis

21 January 2018

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Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188.

21 January 2018

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Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non-L-type Ca2+ channel

21 January 2018

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Different voltage-dependent inhibition by dihydropyridines of human Ca2+ channel splice variants

21 January 2018

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Alternatively spliced IS6 segments of the alpha 1C gene determine the tissue-specific dihydropyridine sensitivity of cardiac and vascular smooth muscle L-type Ca2+ channels

21 January 2018

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Calcium channels: the beta-subunit increases the affinity of dihydropyridine and Ca2+ binding sites of the alpha 1-subunit.

21 January 2018

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Molecular determinants of cardiac Ca2+ channel pharmacology. Subunit requirement for the high affinity and allosteric regulation of dihydropyridine binding

21 January 2018

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Molecular diversity of L-type Ca2+ channel transcripts in human fibroblasts

21 January 2018

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Molecular structures involved in L-type calcium channel inactivation. Role of the carboxyl-terminal region encoded by exons 40-42 in alpha1C subunit in the kinetics and Ca2+ dependence of inactivation

21 January 2018

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Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid

21 January 2018

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Ca2+-sensitive inactivation of L-type Ca2+ channels depends on multiple cytoplasmic amino acid sequences of the alpha1C subunit

21 January 2018

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The roles of the subunits in the function of the calcium channel

21 January 2018

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Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle

21 January 2018

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Primary structure and functional expression from complementary DNA of a brain calcium channel

21 January 2018

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The beta 1-subunit is essential for modulation by protein kinase C of an human and a non-human L-type Ca2+ channel

21 January 2018

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Genomic structure of human L-type Ca2+ channel

21 January 2018

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Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart

21 January 2018

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Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung

21 January 2018

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Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

21 January 2018

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Molecular determinants of drug binding and action on L-type calcium channels

21 January 2018

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Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state

21 January 2018

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Molecular studies on the voltage dependence of dihydropyridine action on L-type Ca2+ channels. Critical involvement of tyrosine residues in motif IIIS6 and IVS6.

21 January 2018

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Calcium binding in the pore of L-type calcium channels modulates high affinity dihydropyridine binding

21 January 2018

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Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels

7 January 2021

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The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines.

7 January 2021

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Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.

7 January 2021

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Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity

7 January 2021

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The block of the expressed L-type calcium channel is modulated by the beta 3 subunit

7 January 2021

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10.1016/S0014-5793(98)00425-6

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9607315%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference