Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice (Q28288250)

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English	Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice	scientific article

Statements

instance of

scholarly article

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title

Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice (English)

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main subject

spinal muscular atrophy

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based on heuristic

inferred from title

muscular atrophy

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based on heuristic

inferred from title

author

Ming-Shiun Tsai

object named as

Ming-Shiun Tsai

series ordinal

2

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Li-Kai Tsai

object named as

Li-Kai Tsai

series ordinal

1

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author name string

Chen-Hung Ting

series ordinal

3

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Hung Li

series ordinal

4

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language of work or name

English

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publication date

November 2008

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published in

Journal of Molecular Medicine

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volume

86

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issue

11

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page(s)

1243-54

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cites work

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Spinal muscular atrophy

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Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy

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Antiepileptic drugs

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An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA).

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Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells

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The SMN complex

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PubMed

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Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene

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Neuropathological analysis in spinal muscular atrophy type II.

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PubMed

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12 December 2020

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SMN mRNA and protein levels in peripheral blood: biomarkers for SMA clinical trials

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PubMed

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12 December 2020

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Valproic acid treatment in six patients with spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

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PubMed

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A mouse model for spinal muscular atrophy

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PubMed

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12 December 2020

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In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate

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PubMed

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12 December 2020

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A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.

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PubMed

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12 December 2020

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Unilateral induction of progenitors in the spinal cord of hSOD1G93A transgenic rats correlates with an asymmetrical hind limb paralysis

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12 December 2020

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In vivo infusions of exogenous growth factors into the fourth ventricle of the adult mouse brain increase the proliferation of neural progenitors around the fourth ventricle and the central canal of the spinal cord

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Valproic Acid Promotes Neurite Outgrowth in PC12 Cells independent from Regulation of the Survival of Motoneuron Protein

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Amyotrophic lateral sclerosis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Correlation between severity and SMN protein level in spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Establishing a standardized therapeutic testing protocol for spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Early response of endogenous adult neural progenitor cells to acute spinal cord injury in mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Cell proliferation and replacement following contusive spinal cord injury

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Intragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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The survival motor neuron protein in spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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inferred from PubMed ID database lookup

Neurofilament accumulation at the motor endplate and lack of axonal sprouting in a spinal muscular atrophy mouse model

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Valproate may improve strength and function in patients with type III/IV spinal muscle atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Valproic acid increases SMN levels in spinal muscular atrophy patient cells.

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stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Restoring Bcl-x(L) levels benefits a mouse model of spinal muscular atrophy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Identification and characterization of a spinal muscular atrophy-determining gene

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a neural stem cell in the adult mammalian central nervous system

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stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line

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stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat5 constitutive activation rescues defects in spinal muscular atrophy

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18649067

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12 December 2020

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Identifiers

DOI

10.1007/S00109-008-0388-1

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Dimensions Publication ID

1050175863

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PubMed publication ID

18649067

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ResearchGate publication ID

51422728

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