Dihydrexidine--the first full dopamine D1 receptor agonist (Q28288584)

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English	Dihydrexidine--the first full dopamine D1 receptor agonist	scientific article

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Europe PubMed Central

title

Dihydrexidine--the first full dopamine D1 receptor agonist (English)

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PMC publication ID

6741759

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

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12 May 2020

main subject

dopamine

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author

Björn Kull

series ordinal

3

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PMC publication ID

6741759

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12 May 2020

author name string

Peter Salmi

series ordinal

1

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PMC publication ID

6741759

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12 May 2020

Ruben Isacson

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2

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Europe PubMed Central

PMC publication ID

6741759

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12 May 2020

language of work or name

English

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publication date

2004

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CNS Neuroscience & Therapeutics

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Europe PubMed Central

PMC publication ID

6741759

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

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12 May 2020

volume

10

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Europe PubMed Central

PMC publication ID

6741759

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

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12 May 2020

issue

3

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Europe PubMed Central

PMC publication ID

6741759

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

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12 May 2020

page(s)

230-242

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Europe PubMed Central

PMC publication ID

6741759

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

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12 May 2020

cites work

Ventral hippocampal dopamine D1 and D2 systems and spatial working memory in rats

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Effect of a selective dopamine D1 agonist (ABT-431) on smoked cocaine self-administration in humans

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PubMed

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12 December 2020

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Dopamine receptors--physiological understanding to therapeutic intervention potential

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PubMed

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12 December 2020

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D(1) dopamine receptor agonists are more effective in alleviating advanced than mild parkinsonism in 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated monkeys

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Reversal of antipsychotic-induced working memory deficits by short-term dopamine D1 receptor stimulation

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PubMed

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12 December 2020

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Sedative effects of the dopamine D1 receptor agonist A 68930 on rat open-field behavior

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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A-68930, a novel, potent dopamine D1 receptor agonist: a microstructural analysis of its effects on feeding and other behaviour in the rat.

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PubMed

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12 December 2020

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Delay-dependent modulation of memory retrieval by infusion of a dopamine D1 agonist into the rat medial prefrontal cortex

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PubMed

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12 December 2020

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Functional relationship among medial prefrontal cortex, nucleus accumbens, and ventral tegmental area in locomotion and reward.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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inferred from PubMed ID database lookup

Parkinson's disease and D1 dopamine receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dopamine and the regulation of cognition and attention

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperthermia induced by the dopamine D1 receptor agonist SK&F38393 in combination with the dopamine D2 receptor agonist talipexole in the rat

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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Linkage of the dopamine receptor D1 gene to attention-deficit/hyperactivity disorder

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 68930 and dihydrexidine inhibit locomotor activity and d-amphetamine-induced hyperactivity in rats: a role of inhibitory dopamine D(1/5) receptors in the prefrontal cortex?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Effects of dopamine D1 receptor full agonists in rats trained to discriminate SKF 38393.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Behavioral effects of selective dopaminergic compounds in rats discriminating cocaine injections

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dopamine receptor mediated hypothermic action of B-HT 920 in rats

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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A68930: a potent agonist selective for the dopamine D1 receptor

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Behavioral effects in the rat of dihydrexidine, a high-potency, full-efficacy D1 dopamine receptor agonist

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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D1 dopamine receptors of NS20Y neuroblastoma cells are functionally similar to rat striatal D1 receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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The effects of selective dopamine receptor agonists and antagonists on body temperature in rats

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine and thermoregulation: an evaluation with special reference to dopaminergic pathways

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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Assessment of grooming and other behavioural responses to the D-1 dopamine receptor agonist SK & F 38393 and its R- and S-enantiomers in the intact adult rat

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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Sniffing, rearing and locomotor responses to the D-1 dopamine agonist R-SK&F 38393 and to apomorphine: differential interactions with the selective D-1 and D-2 antagonists SCH 23390 and metoclopramide

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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The role of dopamine in locomotor activity and learning

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats

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PubMed

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12 December 2020

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"Full" dopamine D1 agonists in human caudate: biochemical properties and therapeutic implications

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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In vivo stimulated dopamine release in the nucleus accumbens: modulation by the prefrontal cortex

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dihydrexidine, a full D1 dopamine receptor agonist, induces rotational asymmetry in hemiparkinsonian monkeys

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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Effects of dihydrexidine, a full dopamine D-1 receptor agonist, on delayed response performance in chronic low dose MPTP-treated monkeys

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dopamine D1 receptors: efficacy of full (dihydrexidine) vs. partial (SKF38393) agonists in primates vs. rodents

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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The role of D1-dopamine receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Social reactivity and D1 dopamine receptors: studies in mice selectively bred for high and low levels of aggression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Evidence for specific involvement of dopamine D1 and D2 receptors in the regulation of body temperature in the rat

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: a potent full dopamine D1 agonist containing a rigid-beta-phenyldopamine pharmacophore

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Spare receptors and intrinsic activity: studies with D1 dopamine receptor agonists.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Alterations in locomotor activity after microinjections of GBR-12909, selective dopamine antagonists or neurotensin into the medial prefrontal cortex

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

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Self-administration of the D1 agonist SKF 82958 is mediated by D1, not D2, receptors

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D1 dopamine receptor mediation of social and nonsocial emotional reactivity in mice: effects of housing and strain difference in motor activity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine, the prefrontal cortex and schizophrenia

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D1 agonist dihydrexidine releases acetylcholine and improves cognitive performance in rats

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychopharmacological distinction between novel full-efficacy "D1-like" dopamine receptor agonists

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydrexidine produces hypothermia in rats via activation of dopamine D1 receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent roles of dopamine D1 and D2/3 receptors in rat thermoregulation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of full D1 dopamine receptor agonists on firing rates in the globus pallidus and substantia nigra pars compacta in vivo: tests for D1 receptor selectivity and comparisons to the partial agonist SKF 38393.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D1 receptor agonists as antiparkinson drugs

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D1 dopamine receptor agonists mediate activation of p38 mitogen-activated protein kinase and c-Jun amino-terminal kinase by a protein kinase A-dependent mechanism in SK-N-MC human neuroblastoma cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

retrieved

12 December 2020

based on heuristic

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Effects of the full dopamine D1 receptor agonist dihydrexidine in Parkinson's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15492773

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12 December 2020

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Identifiers

DOI

10.1111/J.1527-3458.2004.TB00024.X

1 reference

stated in

Europe PubMed Central

PMC publication ID

6741759

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

retrieved

12 May 2020

PMC publication ID

6741759

1 reference

stated in

Europe PubMed Central

PMC publication ID

6741759

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

retrieved

12 May 2020

PubMed publication ID

15492773

1 reference

stated in

Europe PubMed Central

PMC publication ID

6741759

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741759&resulttype=core&format=json

retrieved

12 May 2020

ResearchGate publication ID

8223825

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