Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase (Q28296183)

DNA-damage inducible transcript 3

GOA release 2020-03-11

1 reference

Eukaryotic translation initiation factor 2 alpha kinase 3

GOA release 2020-03-11

1 reference

Reversible phosphorylation of eukaryotic initiation factor 2 alpha in response to endoplasmic reticular signaling

GOA release 2020-03-11

D Ron

3

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author name string

H P Harding

series ordinal

1

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Y Zhang

series ordinal

2

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language of work or name

English

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publication date

21 January 1999

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published in

Nature

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volume

397

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issue

6716

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page(s)

271-4

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cites work

1 reference

Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells

21 January 2018

1 reference

Mammalian stress response: induction of the glucose-regulated protein family

21 January 2018

1 reference

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

21 January 2018

1 reference

Protein folding in the cell

21 January 2018

1 reference

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

21 January 2018

1 reference

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

21 January 2018

1 reference

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

21 January 2018

1 reference

Splicing together the unfolded-protein response

21 January 2018

1 reference

The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stress

21 January 2018

1 reference

Calcium depletion from the endoplasmic reticulum activates the double-stranded RNA-dependent protein kinase (PKR) to inhibit protein synthesis

21 January 2018

1 reference

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

21 January 2018

1 reference

Activation of the double-stranded RNA-regulated protein kinase by depletion of endoplasmic reticular calcium stores

21 January 2018

1 reference

Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinase

21 January 2018

1 reference

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

21 January 2018

1 reference

Independent signaling of grp78 gene transcription and phosphorylation of eukaryotic initiator factor 2 alpha by the stressed endoplasmic reticulum

21 January 2018

1 reference

The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation

21 January 2018

1 reference

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

21 January 2018

1 reference

Use of vertical slab isoelectric focusing and immunoblotting to evaluate steady-state phosphorylation of eIF2 alpha in cultured cells

21 January 2018

1 reference

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

21 January 2018

1 reference

Regulation of translational initiation during cellular responses to stress

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

1 reference