Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment (Q28348367)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532928%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment (English)

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10 November 2019

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2

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10 November 2019

Martin A Schwartz

5

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10 November 2019

author name string

E Tzima

1

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10 November 2019

S J Shattil

3

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10 November 2019

S Chien

4

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10 November 2019

language of work or name

English

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publication date

1 September 2001

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10 November 2019

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10 November 2019

volume

20

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10 November 2019

issue

17

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10 November 2019

page(s)

4639-4647

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Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases

10 November 2019

cites work

1 reference

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Focal adhesions, contractility, and signaling

20 March 2017

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

20 March 2017

1 reference

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Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

7 April 2017

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The protein tyrosine phosphatase Shp-2 regulates RhoA activity

7 April 2017

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Signaling networks linking integrins and rho family GTPases.

29 September 2017

1 reference

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Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

29 September 2017

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Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

29 September 2017

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Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand

29 September 2017

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Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress

29 September 2017

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Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

29 September 2017

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A role for Cdc42 in macrophage chemotaxis

29 September 2017

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Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. Essential role for a herbimycin-sensitive kinase

29 September 2017

1 reference

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Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain

29 September 2017

1 reference

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Endothelial cell adhesion in real time. Measurements in vitro by tandem scanning confocal image analysis

29 September 2017

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Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility

29 September 2017

1 reference

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Regulation and function of the Rho subfamily of small GTPases

29 September 2017

1 reference

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Quantitative studies of endothelial cell adhesion. Directional remodeling of focal adhesion sites in response to flow forces

29 September 2017

1 reference

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Adhesive ligand binding to integrin alpha IIb beta 3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK

29 September 2017

1 reference

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Endothelial cell adhesive receptors.

29 September 2017

1 reference

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Flow-mediated endothelial mechanotransduction

29 September 2017

1 reference

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Integrin cytoplasmic domains mediate inside-out signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125600

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

29 September 2017

1 reference

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Distribution of fetal bovine serum fibronectin and endogenous rat cell fibronectin in extracellular matrix

29 September 2017

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Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125600

Are changes in integrin affinity and conformation overemphasized?

2 June 2018

1 reference

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Role of integrins in cellular responses to mechanical stress and adhesion

2 June 2018

1 reference

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Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction

2 June 2018

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Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway

2 June 2018

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Atheroma and arterial wall shear. Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis.

2 June 2018

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The elongation and orientation of cultured endothelial cells in response to shear stress.

2 June 2018

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Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells

2 June 2018

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Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands

2 June 2018

1 reference

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Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

27 November 2018

1 reference

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Functional relevance during lymphocyte migration and cellular localization of activated beta1 integrins

27 November 2018

1 reference

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Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125600

Involvement of rho p21 in cyclic strain-induced tyrosine phosphorylation of focal adhesion kinase (pp125FAK), morphological changes and migration of endothelial cells

27 November 2018

1 reference

12 December 2020

Integrin signaling transduces shear stress--dependent vasodilation of coronary arterioles

1 reference

12 December 2020

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

1 reference

12 December 2020

Shear stress induces spatial reorganization of the endothelial cell cytoskeleton

1 reference

12 December 2020

Two-stage activation for alpha5beta1 integrin binding to surface-adsorbed fibronectin

1 reference

12 December 2020

Mechanical sensing mechanisms: shear stress and endothelial cells

1 reference

12 December 2020

Endothelial cell signaling and cytoskeletal changes in response to shear stress

1 reference

12 December 2020

Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteins

1 reference

12 December 2020

α v β 3 Integrin Expression in Normal and Atherosclerotic Artery

1 reference

12 December 2020

Arterial Wall Shear and Distribution of Early Atheroma in Man

1 reference

12 December 2020

The removal of extracellular fibronectin from areas of cell-substrate contact

1 reference

12 December 2020

Response of cultured endothelial cells to steady flow

1 reference

12 December 2020

Flow effects on prostacyclin production by cultured human endothelial cells

1 reference

12 December 2020

MAP kinase activation by flow in endothelial cells. Role of beta 1 integrins and tyrosine kinases

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/20.17.4639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532928%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

10 November 2019

5006684

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532928%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

11532928

1 reference