Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I (Q28378884)

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English	Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I	scientific article

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scholarly article

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Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I (English)

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author name string

J L Zhang

1

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P L Sharma

2

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C J Li

3

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B J Dezube

4

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A B Pardee

5

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C S Crumpacker

6

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language of work or name

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publication date

May 1997

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Antimicrobial Agents and Chemotherapy

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41

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5

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977-81

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Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

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Inhibition of Human Immunodeficiency Virus (HTV-1) Replication In Vitro by Noncytotoxic Doses of Camptothecin, a Topoisomerase I Inhibitor

1 reference

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7 April 2017

Human immunodeficiency virus type 1 reverse transcriptase: enhancement of activity by interaction with cellular topoisomerase I.

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29 September 2017

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.

1 reference

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29 September 2017

The NF-kappa B binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity.

1 reference

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29 September 2017

Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I.

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Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites

1 reference

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Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection

1 reference

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The topoisomerase I inhibitor, camptothecin, inhibits equine infectious anemia virus replication in chronically infected CF2Th cells

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Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes

1 reference

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29 September 2017

Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor

1 reference

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29 September 2017

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin

1 reference

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2 June 2018

DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues

1 reference

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2 June 2018

Patterns of strongly protein-associated simian virus 40 DNA replication intermediates resulting from exposures to specific topoisomerase poisons

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Role of DNA topoisomerase I in the replication of herpes simplex virus type 2.

1 reference

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2 June 2018

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

1 reference

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2 June 2018

Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells

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2 June 2018

Inhibition of HIV-1 RNA production by the diphtheria toxin-related IL-2 fusion proteins DAB486IL-2 and DAB389IL-2.

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2 June 2018

Effect of P-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue.

1 reference

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2 June 2018

Synergistic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864)

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9145855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/9145855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9145855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.41.5.977

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