Interleukin 12 a key immunoregulatory cytokine in infection applications (Q28395500)

Europe PubMed Central

23 March 2019

Europe PubMed Central

20 November 2019

Europe PubMed Central

on focus list of Wikimedia project

26 September 2020

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cites work

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19 March 2017

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

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29 September 2017

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Interleukin-35: odd one out or part of the family?

29 September 2017

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29 September 2017

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29 September 2017

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Influenza virus vaccination induces interleukin-12/23 receptor beta 1 (IL-12/23R beta 1)-independent production of gamma interferon (IFN-gamma) and humoral immunity in patients with genetic deficiencies in IL-12/23R beta 1 or IFN-gamma receptor I.

29 September 2017

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29 September 2017

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Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The role of IL-12, IL-23 and IFN-gamma in immunity to viruses

29 September 2017

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An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells

29 September 2017

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The biology of IL-12: coordinating innate and adaptive immune responses

29 September 2017

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Novel IL-12 family members shed light on the orchestration of Th1 responses

29 September 2017

1 reference

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T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

29 September 2017

1 reference

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c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Intranasal therapy with an adenoviral vector containing the murine interleukin-12 gene eradicates osteosarcoma lung metastases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Selective suppression of interleukin-12 induction after macrophage receptor ligation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Staphylococcus aureus invasion of bovine mammary epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

IL-12 in conjunction with dendritic cells enhances antiviral CD8+ CTL responses in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Interleukin-12: a bridge between innate resistance and adaptive immunity with a role in infection and acquired immunodeficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

The efficacy of influenza vaccine in elderly persons. A meta-analysis and review of the literature.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Gamma interferon, cytokine-induced macrophage activation, and antimicrobial host defense. In vitro, in animal models, and in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. Evidence for different kinetics and recognition of a wide spectrum of protein antigens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Critical role of corneal Langerhans cells in the CD4- but not CD8-mediated immunopathology in herpes simplex virus-1-infected mouse corneas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Interleukin-12 treatment restores normal resistance to bacterial challenge after burn injury

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

The impact of femur fracture with associated soft tissue injury on immune function and intestinal permeability

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Characterization of anti-mouse IL-12 monoclonal antibodies and measurement of mouse IL-12 by ELISA.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

2 June 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS11030789

Molecular cloning and functional characterization of guinea pig IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS11030789

Recombinant interleukin-12 and interleukin-18 antitumor therapy in a guinea-pig hepatoma cell implant model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS11030789

Biomimetic nanostructured materials: inherent reversible stabilization of polypeptide microcapsules.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS11030789

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS11030789

Interleukin-12 protects thermally injured mice from herpes simplex virus type 1 infection.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869233

Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells

27 November 2018

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12 December 2020

Lymphocyte-specific chemokine receptor CXCR3: regulation, chemokine binding and gene localization

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12 December 2020

Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells

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12 December 2020

Proinflammatory kupffer cell alterations after femur fracture trauma and sepsis in rats

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12 December 2020

Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo

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12 December 2020

Defects of monocyte interleukin 12 production and humoral immunity in Whipple's disease

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12 December 2020

Staphylococcus aureus infection of mouse or human osteoblasts induces high levels of interleukin-6 and interleukin-12 production

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12 December 2020

Pilot study of subcutaneous recombinant human interleukin 12 in metastatic melanoma

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12 December 2020

Elusive HIV-suppressor factors found

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12 December 2020

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12 December 2020

Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection

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12 December 2020

In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: induction of tumor regression and potent antitumor immunity

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12 December 2020

Internalization of Staphylococcus aureus by cultured osteoblasts

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12 December 2020

Identifiers

DOI

10.3390/IJMS11030789

1 reference

1 reference

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PubMed publication ID

20479986

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