Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening (Q28472268)

1

0 references

Orzala Sharif

2

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Paul Anderson

3

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Buu Tu

4

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Genevieve Welch

5

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Yingyao Zhou

6

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Jeremy S Caldwell

7

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Ingo H Engels

8

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Achim Brinker

Creative Commons Attribution 4.0 International

9

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language of work or name

English

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publication date

17 December 2009

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published in

PLOS One

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volume

4

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issue

12

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page(s)

e8348

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copyright license

start time

17 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

Cytoscape

object named as

Cytoscape

2 references

Europe PubMed Central

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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29 September 2017

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29 September 2017

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Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophy

29 September 2017

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29 September 2017

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HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

29 September 2017

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A deep intronic mutation in FGB creates a consensus exonic splicing enhancer motif that results in afibrinogenemia caused by aberrant mRNA splicing, which can be corrected in vitro with antisense oligonucleotide treatment.

29 September 2017

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29 September 2017

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A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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PTC124 targets genetic disorders caused by nonsense mutations

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Entries in the Leiden Duchenne muscular dystrophy mutation database: an overview of mutation types and paradoxical cases that confirm the reading-frame rule

29 September 2017

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Functional analysis of 114 exon-internal AONs for targeted DMD exon skipping: indication for steric hindrance of SR protein binding sites

29 September 2017

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Regulated cellular partitioning of SR protein-specific kinases in mammalian cells

29 September 2017

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29 September 2017

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Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Disruption of the splicing enhancer sequence within exon 27 of the dystrophin gene by a nonsense mutation induces partial skipping of the exon and is responsible for Becker muscular dystrophy

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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An intact cysteine-rich domain is required for dystrophin function

29 September 2017

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Reconstruction of the 2.4 Mb human DMD-gene by homologous YAC recombination

29 September 2017

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29 September 2017

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Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones

29 September 2017

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy.

2 June 2018

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In vivo comparison of 2'-O-methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Division of labor: minor splicing in the cytoplasm.

27 November 2018

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Dystrophin levels as low as 30% are sufficient to avoid muscular dystrophy in the human

27 November 2018

1 reference

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Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors.

27 November 2018

1 reference

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An exon skipping-associated nonsense mutation in the dystrophin gene uncovers a complex interplay between multiple antagonistic splicing elements

27 November 2018

1 reference

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Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

27 November 2018

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A novel histone deacetylase inhibitor, Scriptaid, induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells

27 November 2018

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Alternative splicing of type II procollagen exon 2 is regulated by the combination of a weak 5' splice site and an adjacent intronic stem-loop cis element

27 November 2018

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27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791862

Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791862

Long mutant dystrophins and variable phenotypes: evasion of nonsense-mediated decay?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791862

Transcriptional regulation and function during the human cell cycle

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791862

Dystrophin nonsense mutations can generate alternative rescue transcripts in lymphocytes

27 November 2018

1 reference

12 December 2020

The effects of glucocorticoid therapy on the inflammatory and dendritic cells in muscular dystrophies

1 reference

12 December 2020

Protein- and mRNA-based phenotype-genotype correlations in DMD/BMD with point mutations and molecular basis for BMD with nonsense and frameshift mutations in the DMD gene

1 reference

12 December 2020

Local dystrophin restoration with antisense oligonucleotide PRO051

1 reference

12 December 2020

Mitotic arrest by benzimidazole analogs in human lymphocyte cultures

1 reference

12 December 2020

Prednisone treatment in Duchenne muscular dystrophy. Long-term benefit

1 reference

12 December 2020

Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A

1 reference

12 December 2020

Prevalence and incidence of Becker muscular dystrophy

1 reference

12 December 2020

[Influences of 5'-deoxy-5-fluorouridine (5'-DFUR) on cell cycle in patients with breast cancer]

1 reference

12 December 2020

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

1 reference

12 December 2020

Localization of the RNA-binding proteins Staufen1 and Staufen2 at the mammalian neuromuscular junction

1 reference

12 December 2020

A comparison of the mechanisms of action of VP-16-213 and podophyllotoxin

1 reference

12 December 2020

Dystrophin gene transcripts skipping the mdx mutation

1 reference

12 December 2020

Novel nonsense mutation (C-->A nt 10512) in exon 72 of dystrophin gene leading to exon skipping in a patient with a mild dystrophinopathy

1 reference

12 December 2020