The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation (Q28504536)

24 January 2017

title

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation (English)

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24 January 2017

main subject

Programmed cell death 4

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Eukaryotic translation initiation factor 4, gamma 2

GOA release 2020-03-11

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GOA release 2020-03-11

8

Nahum Sonenberg

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24 January 2017

Sylvain Costes

6

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author name string

Hsin-Sheng Yang

1

1 reference

24 January 2017

Aaron P. Jansen

2

1 reference

24 January 2017

Anton A. Komar

3

1 reference

24 January 2017

Xiaojing Zheng

4

1 reference

24 January 2017

William C. Merrick

5

1 reference

24 January 2017

Stephen J. Lockett

7

1 reference

24 January 2017

Nancy H. Colburn

9

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24 January 2017

language of work or name

English

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publication date

1 January 2003

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Molecular and Cellular Biology

24 January 2017

published in

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24 January 2017

volume

23

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24 January 2017

issue

1

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24 January 2017

page(s)

26–37

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Up-regulation of PDCD4 in senescent human diploid fibroblasts

24 January 2017

cites work

1 reference

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Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo

19 March 2017

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The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

19 March 2017

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A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation

19 March 2017

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Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation

19 March 2017

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

19 March 2017

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Novel human PDCD4 (H731) gene expressed in proliferative cells is expressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibody

19 March 2017

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Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII

19 March 2017

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Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase

19 March 2017

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Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H

19 March 2017

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Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A

19 March 2017

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Translation initiation factor eIF-4A1 mRNA is consistently overexpressed in human melanoma cells in vitro

19 March 2017

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Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death

19 March 2017

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The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A

19 March 2017

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The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding Proteins

19 March 2017

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Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A

19 March 2017

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Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

19 March 2017

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Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation

7 April 2017

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7 April 2017

Birth of the D-E-A-D box

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

7 April 2017

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7 April 2017

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Translation initiation and its deregulation during tumorigenesis

7 April 2017

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Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

29 September 2017

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Translation initiation factor eIF-4G is immunogenic, overexpressed, and amplified in patients with squamous cell lung carcinoma

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region

29 September 2017

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Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase.

29 September 2017

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A signaling pathway to translational control

29 September 2017

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The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis

29 September 2017

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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

29 September 2017

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The mouse protein synthesis initiation factor 4A gene family includes two related functional genes which are differentially expressed.

29 September 2017

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The ATP-dependent interaction of eukaryotic initiation factors with mRNA.

29 September 2017

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mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E

29 September 2017

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Molecular cloning of the genes suppressed in RVC lymphoma cells by topoisomerase inhibitors

29 September 2017

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Extracellular Matrix-derived Peptide Binds to αvβ3Integrin and Inhibits Angiogenesis

2 June 2018

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Translational control of the cdc25 cell cycle phosphatase: a molecular mechanism coupling mitosis to cell growth

27 November 2018

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Influence of 5' proximal secondary structure on the translational efficiency of eukaryotic mRNAs and on their interaction with initiation factors

27 November 2018

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12 December 2020

Novel eIF4G domain homologues linking mRNA translation with nonsense-mediated mRNA decay

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12 December 2020

Characterization of the two eIF4A-binding sites on human eIF4G-1

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12 December 2020

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12 December 2020

Biochemical and kinetic characterization of the RNA helicase activity of eukaryotic initiation factor 4A

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12 December 2020