Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue (Q28506834)

24 January 2017

title

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue (English)

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24 January 2017

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GOA release 2020-03-11

author

Virginia E Papaioannou

object named as

V. E. Papaioannou

4

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author name string

S. Zeitlin

1

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24 January 2017

J. P. Liu

2

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24 January 2017

D. L. Chapman

3

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24 January 2017

A. Efstratiadis

5

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24 January 2017

language of work or name

English

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publication date

1 October 1995

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24 January 2017

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24 January 2017

volume

11

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24 January 2017

issue

2

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24 January 2017

page(s)

155–163

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Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

24 January 2017

cites work

1 reference

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

21 April 2017

1 reference

Cell death in health and disease: the biology and regulation of apoptosis

21 April 2017

1 reference

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

21 April 2017

1 reference

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

Genetics and molecular biology of Huntington's disease

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

https://api.crossref.org/works/10.1038%2FNG1095-155

1 reference

7 January 2021

The functional anatomy of basal ganglia disorders

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

DNA End Labeling (TUNEL) in Huntington's Disease and Other Neuropathological Conditions

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Dynamic mutations: a new class of mutations causing human disease

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Dynamic mutations on the move

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Trinucleotide repeat length instability and age of onset in Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent.

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15.

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

A CCG repeat polymorphism adjacent to the CAG repeat in the Huntington disease gene: implications for diagnostic accuracy and predictive testing

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

A single allele from the polymorphic CCG rich sequence immediately 3' to the unstable CAG trinucleotide in the IT15 cDNA shows almost complete disequilibrium with Huntington's disease chromosomes in the Scottish population

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Characterization and localization of the Huntington disease gene product

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Huntington's disease gene: regional and cellular expression in brain of normal and affected individuals

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Transcriptional activation modulated by homopolymeric glutamine and proline stretches

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Mouse Huntington's disease gene homolog (Hdh).

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Activation of apoptosis in early mouse embryos by 2'-deoxyadenosine exposure

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Development, morphology, and function of the yolk-sac placenta of laboratory rodents

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Cell lineage analysis of the primitive and visceral endoderm of mouse embryos cultured in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Death before birth: clues from gene knockouts and mutations

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Murine FGFR-1 is required for early postimplantation growth and axial organization

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Dicing with death: dissecting the components of the apoptosis machinery.

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Is compensatory growth a complicating factor in mouse teratology?

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Growth and its control in early mammalian development

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Social controls on cell survival and cell death

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021

A method to isolate DNA from small archival tissue samples for p53 gene analysis

1 reference

https://api.crossref.org/works/10.1038%2FNG1095-155

7 January 2021