The PrP-like protein Doppel binds copper (Q28506863)

24 January 2017

title

The PrP-like protein Doppel binds copper (English)

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Prion like protein doppel

24 January 2017

main subject

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GOA release 2020-03-11

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11

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Stanley B. Prusiner

7

object named as

Stanley B. Prusiner

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24 January 2017

9

Jonathan M. Goldberg

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ORCID Public Data File 2021

24 January 2017

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author name string

Kefeng Qin

1

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24 January 2017

Janaky Coomaraswamy

2

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24 January 2017

Peter Mastrangelo

3

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24 January 2017

Ying Yang

4

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24 January 2017

Stan Lugowski

5

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24 January 2017

Chris Petromilli

6

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24 January 2017

Paul E. Fraser

8

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24 January 2017

Avijit Chakrabartty

10

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24 January 2017

language of work or name

English

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publication date

14 March 2003

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Journal of Biological Chemistry

24 January 2017

published in

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24 January 2017

volume

278

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24 January 2017

issue

11

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24 January 2017

page(s)

8888–8896

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Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting

24 January 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M210875200

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

21 January 2018

1 reference

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21 January 2018

1 reference

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Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Doppel-induced cerebellar degeneration in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

A cellular gene encodes scrapie PrP 27-30 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

NEUROBIOLOGY:PrP's Double Causes Trouble

21 January 2018

1 reference

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Signal transduction through prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Prion Protein-Deficient Cells Show Altered Response to Oxidative Stress Due to Decreased SOD-1 Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Prion protein protects human neurons against Bax-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

The cellular prion protein binds copper in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Prion protein selectively binds copper(II) ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Copper stimulates endocytosis of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Two-octapeptide repeat deletion of prion protein associated with rapidly progressive dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Creutzfeldt-Jakob disease associated with a deletion of two repeats in the prion protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Two different neurodegenerative diseases caused by proteins with similar structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Location and properties of metal-binding sites on the human prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

XAFS study of the high-affinity copper-binding site of human PrP(91-231) and its low-resolution structure in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Electron paramagnetic resonance evidence for binding of Cu(2+) to the C-terminal domain of the murine prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

B lymphocytes and neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Normal prion protein has an activity like that of superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

Prion protein binds copper within the physiological concentration range

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

The impact of calcium, magnesium, zinc, and copper in blood and seminal plasma on semen parameters in men

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210875200

The cellular prion protein binds copper in vivo

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M210875200

Identifiers

DOI

10.1074/JBC.M210875200

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