Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets (Q28507344)

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

GOA release 2020-03-11

Glucagon

1 reference

Signal transducer and activator of transcription 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Elaine Vieira

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Angel Nadal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Ivan Quesada

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

A Gonzalez

3

1 reference

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20 January 2020

publication date

14 January 2011

1 reference

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20 January 2020

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

54

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

4

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

843-851

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

20 January 2020

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Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes.

21 January 2018

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Homologous and heterologous asynchronicity between identified alpha-, beta- and delta-cells within intact islets of Langerhans in the mouse

21 January 2018

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Glucagon physiology and pathophysiology in the light of new advances

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The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications

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Recent advances in understanding leptin signaling and leptin resistance

21 January 2018

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Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice

21 January 2018

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Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice

21 January 2018

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Inhibitory effects of leptin on pancreatic alpha-cell function.

21 January 2018

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Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus

21 January 2018

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Inhibition of preproinsulin gene expression by leptin induction of suppressor of cytokine signaling 3 in pancreatic beta-cells

21 January 2018

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Glucagon and Insulin Relationships in Genetically Diabetic (db/db) and in Streptozotocin-Induced Diabetic Mice

21 January 2018

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The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

21 January 2018

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Leptin therapy in insulin-deficient type I diabetes

21 January 2018

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Making insulin-deficient type 1 diabetic rodents thrive without insulin

21 January 2018

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Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle

21 January 2018

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The real-time polymerase chain reaction

21 January 2018

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STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX

21 January 2018

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PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

21 January 2018

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FoxO1 is required for the regulation of preproglucagon gene expression by insulin in pancreatic alphaTC1-9 cells

21 January 2018

1 reference

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Glucose dependence of the regulated secretory pathway in alphaTC1-6 cells

21 January 2018

1 reference

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Glucose Regulates Proinsulin and Prosomatostatin But Not Proglucagon Messenger Ribonucleic Acid Levels in Rat Pancreatic Islets

21 January 2018

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Intracellular signalling pathways activated by leptin

21 January 2018

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STAT3 targets the regulatory regions of gluconeogenic genes in vivo

21 January 2018

1 reference

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Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization

21 January 2018

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Melanocortin-independent effects of leptin on hepatic glucose fluxes

21 January 2018

1 reference

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Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling.

21 January 2018

1 reference

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Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

21 January 2018

1 reference

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Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels

21 January 2018

1 reference

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Loss of insulin-induced inhibition of glucagon gene transcription in hamster pancreatic islet alpha cells by long-term insulin exposure

21 January 2018

1 reference

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Role of Stat3 in regulating p53 expression and function

21 January 2018

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Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo

21 January 2018

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Leveraging leptin for type I diabetes?

21 January 2018

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Glucose Induces Opposite Intracellular Ca2+Concentration Oscillatory Patterns in Identified α- and β-Cells Within Intact Human Islets of Langerhans

21 January 2018

1 reference

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Glucagon and insulin secretion by islets of lean and obese (ob/ob) mice

21 January 2018

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12 December 2020

Glucose regulates proinsulin and prosomatostatin but not proglucagon messenger ribonucleic acid levels in rat pancreatic islets

1 reference

12 December 2020

Regulation of human insulin gene transcription by glucose, epinephrine, and somatostatin.

1 reference

12 December 2020

Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes

1 reference

12 December 2020

Stat3 mediates interleukin-6 [correction of interelukin-6] inhibition of human endothelial nitric-oxide synthase expression

1 reference

12 December 2020

Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway

1 reference

12 December 2020

10.1007/S00125-010-2024-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234744%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 January 2020

1042609754

0 references

2 references

24 January 2017