Vascular endothelial growth factor A (Q28560410)

Vascular endothelial growth factor, heparin-binding domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Vascular endothelial growth factor, heparin-binding domain, protein family

1 reference

inferred from protein domain or family

PDGF/VEGF domain, protein family

1 reference

inferred from protein domain or family

Platelet-derived growth factor, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

vascular endothelial growth factor receptor binding

TAS

growth factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

14 February 2019

HMG CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

growth factor binding

IPI

1 reference

14 February 2019

Heparin affin regulatory peptide/pleiotrophin negatively affects diverse biological activities in C6 glioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

IPI

chemoattractant activity

Vascular endothelial growth factor participates in modulating the C6 glioma-induced migration of rat bone marrow-derived mesenchymal stem cells and upregulates their vascular cell adhesion molecule-1 expression

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

protein homodimerization activity

1 reference

14 February 2019

Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

vascular endothelial growth factor receptor 1 binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

vascular endothelial growth factor receptor 2 binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

basement membrane

1 reference

14 February 2019

VEGF-induced mobilization of caveolae and increase in permeability of endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

extracellular space

Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

vesicle

1 reference

14 February 2019

Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

biological process

angiogenesis

Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

TAS

14 February 2019

Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

blood vessel remodeling

1 reference

14 February 2019

Vascular endothelial growth factor is required for coronary collateral growth in the rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

sprouting angiogenesis

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

female pregnancy

1 reference

14 February 2019

Glucocorticoids prevent the normal increase in placental vascular endothelial growth factor expression and placental vascularity during late pregnancy in the rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

human ageing

1 reference

14 February 2019

Normal aging involves altered expression of growth factors in the rat choroid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of cell population proliferation

TAS

response to cold

1 reference

14 February 2019

Cold-induced mRNA expression of angiogenic factors in rat brown adipose tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of signal transduction

1 reference

14 February 2019

Coordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

hyaluronan metabolic process

1 reference

14 February 2019

Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of protein-containing complex assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

response to estradiol

1 reference

14 February 2019

Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

response to progesterone

1 reference

14 February 2019

Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

response to vitamin A

1 reference

14 February 2019

The wound healing effects of vitamin A eye drops after a corneal alkali burn in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

tube formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

vascular endothelial growth factor signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

wound healing

1 reference

14 February 2019

Analysis of gene expression profiles in tympanic membrane following perforation using PCR Array in rats--preliminary investigation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

T-helper 1 type immune response

1 reference

14 February 2019

Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

negative regulation of programmed cell death

1 reference

14 February 2019

Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of vascular permeability

1 reference

14 February 2019

Activation of the stress protein response prevents the development of pulmonary edema by inhibiting VEGF cell signaling in a model of lung ischemia-reperfusion injury in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

cellular response to fibroblast growth factor stimulus

1 reference

14 February 2019

Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

3 references

14 February 2019

14 February 2019

The therapeutic effect of vascular endothelial growth factor gene- or heme oxygenase-1 gene-modified endothelial progenitor cells on neovascularization of rat hindlimb ischemia model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

negative regulation of bone resorption

1 reference

14 February 2019

Increase of both angiogenesis and bone mass in response to exercise depends on VEGF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Hypoxia induces myocyte-dependent COX-2 regulation in endothelial cells: role of VEGF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

vascular endothelial growth factor receptor signaling pathway

mRNA stabilization

1 reference

14 February 2019

Hypoxia induces myocyte-dependent COX-2 regulation in endothelial cells: role of VEGF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

lung alveolus development

1 reference

14 February 2019

Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of smooth muscle cell proliferation

1 reference

14 February 2019

Endogenous VEGF-A is responsible for mitogenic effects of MCP-1 on vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of peptidyl-tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

positive chemotaxis

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

induction of positive chemotaxis

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

response to folic acid

1 reference

14 February 2019

Folic acid supplementation affects ROS scavenging enzymes, enhances Vegf-A, and diminishes apoptotic state in yolk sacs of embryos of diabetic rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

positive regulation of focal adhesion assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

cell chemotaxis

1 reference

14 February 2019

Vascular endothelial growth factor participates in modulating the C6 glioma-induced migration of rat bone marrow-derived mesenchymal stem cells and upregulates their vascular cell adhesion molecule-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

positive regulation of mast cell chemotaxis

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

angiogenesis involved in coronary vascular morphogenesis

1 reference

14 February 2019

Vascular endothelial growth factor and basic fibroblast growth factor differentially modulate early postnatal coronary angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

response to oxygen levels

1 reference

14 February 2019

Differential expression of vascular endothelial growth factor implies the limbal origin of pterygia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

response to dexamethasone

1 reference

14 February 2019

Glucocorticoids prevent the normal increase in placental vascular endothelial growth factor expression and placental vascularity during late pregnancy in the rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

cellular response to dexamethasone stimulus

1 reference

14 February 2019

Differential downregulation of vascular endothelial growth factor by dexamethasone in normoxic and hypoxic rat glioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

motor neuron migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

14 February 2019

positive regulation of cold-induced thermogenesis

1 reference

14 February 2019

Autocrine effect of vascular endothelial growth factor-A is essential for mitochondrial function in brown adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

negative regulation of neuron death

1 reference

14 February 2019

Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16612

1 reference

Platelet-derived growth factor, conserved site

1 reference

Vascular endothelial growth factor, heparin-binding domain

1 reference