The fragile X mental retardation protein inhibits translation via interacting with mRNA (Q28588486)

31 January 2017

title

The fragile X mental retardation protein inhibits translation via interacting with mRNA (English)

1 reference

Synaptic functional regulator FMR1

31 January 2017

main subject

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GOA release 2020-03-11

author name string

Z. Li

1

1 reference

31 January 2017

Y. Zhang

2

1 reference

31 January 2017

L. Ku

3

1 reference

31 January 2017

K. D. Wilkinson

4

1 reference

31 January 2017

S. T. Warren

5

1 reference

31 January 2017

Y. Feng

6

1 reference

31 January 2017

language of work or name

English

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publication date

1 June 2001

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31 January 2017

published in

Nucleic Acids Research

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31 January 2017

volume

29

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31 January 2017

issue

11

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31 January 2017

page(s)

2276–2283

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Evidence that fragile X mental retardation protein is a negative regulator of translation

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex

17 March 2017

1 reference

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A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The STAR protein QKI-6 is a translational repressor

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis

17 March 2017

1 reference

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Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

17 March 2017

1 reference

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Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Translational control in mammalian cells

17 March 2017

2 references

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17 March 2017

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Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains

6 April 2017

1 reference

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Understanding the molecular basis of fragile X syndrome

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans

29 September 2017

1 reference

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RNA-Protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate

29 September 2017

1 reference

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mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.

29 September 2017

1 reference

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Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Advances in molecular analysis of fragile X syndrome

29 September 2017

1 reference

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Quantitative comparison of FMR1 gene expression in normal and premutation alleles

29 September 2017

1 reference

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The human 18S ribosomal RNA gene: evolution and stability

29 September 2017

1 reference

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Molecular evolution of human and rabbit beta-globin mRNAs

29 September 2017

1 reference

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The molecular basis of fragile X syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

FMRP is associated to the ribosomes via RNA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Translational regulation of myelin basic protein synthesis

3 June 2018

1 reference

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(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

Human and murine FMR-1: alternative splicing and translational initiation downstream of the CGG-repeat

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55699

The major core protein of messenger ribonucleoprotein particles (p50) promotes initiation of protein biosynthesis in vitro

27 November 2018

1 reference

12 December 2020

A heterogeneous set of FMR1 proteins is widely distributed in mouse tissues and is modulated in cell culture

1 reference

12 December 2020

The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals

1 reference

12 December 2020

The fragile X syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/29.11.2276

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