Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function. (Q28594348)

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30 December 2019

title

Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function (English)

1 reference

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Myosin, heavy polypeptide 6, cardiac muscle, alpha

30 December 2019

main subject

molecular motor

0 references

1 reference

GOA release 2020-03-11

dilated cardiomyopathy

1 reference

3

1 reference

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30 December 2019

Martin J. Lohse

8

1 reference

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30 December 2019

11

J G Seidman

1 reference

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30 December 2019

10

Christine E Seidman

1 reference

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30 December 2019

6

David A Conner

1 reference

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30 December 2019

1

Joachim P Schmitt

1 reference

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30 December 2019

7

Ulrike Mende

1 reference

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30 December 2019

author name string

Amy Armstrong

4

1 reference

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30 December 2019

Andrea Frederico

5

1 reference

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30 December 2019

David Warshaw

9

1 reference

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30 December 2019

Edward P Debold

2

1 reference

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30 December 2019

language of work or name

English

0 references

publication date

18 September 2006

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

1 reference

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30 December 2019

volume

103

1 reference

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30 December 2019

issue

39

1 reference

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30 December 2019

page(s)

14525-14530

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Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype

30 December 2019

cites work

1 reference

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Molecular mechanics of mouse cardiac myosin isoforms

17 March 2017

1 reference

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

17 March 2017

1 reference

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The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

17 March 2017

1 reference

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Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

17 March 2017

1 reference

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Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy

17 March 2017

1 reference

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Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene

17 March 2017

1 reference

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A mouse model of familial hypertrophic cardiomyopathy

17 March 2017

1 reference

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Structure of the actin-myosin complex and its implications for muscle contraction

17 March 2017

1 reference

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The Genetic Basis for Cardiomyopathy

17 March 2017

1 reference

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Slip sliding away: load-dependence of velocity generated by skeletal muscle myosin molecules in the laser trap.

22 April 2017

1 reference

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The genetic basis for cardiac remodeling

29 September 2017

1 reference

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Transgenesis and cardiac energetics: new insights into cardiac metabolism

29 September 2017

1 reference

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A decade of discoveries in cardiac biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599993

Myosin isoforms show unique conformations in the actin-bound state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599993

Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599993

Molecular diagnosis of myocardial disease

29 September 2017

1 reference

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Molecular mechanisms of inherited cardiomyopathies

29 September 2017

1 reference

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The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599993

The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599993

Hypertrophic cardiomyopathy: a systematic review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599993

R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level

29 September 2017

1 reference

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An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy

29 September 2017

1 reference

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Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy

29 September 2017

1 reference

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Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap

29 September 2017

1 reference

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Calcium regulation of thin filament movement in an in vitro motility assay

29 September 2017

1 reference

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The essential light chain is required for full force production by skeletal muscle myosin

29 September 2017

1 reference

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Structural interpretation of the mutations in the beta-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy

29 September 2017

1 reference

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Smooth muscle myosin cross-bridge interactions modulate actin filament sliding velocity in vitro

29 September 2017

1 reference

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Computer-assisted tracking of actin filament motility

29 September 2017

1 reference

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Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

3 June 2018

1 reference

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Novel mutations in sarcomeric protein genes in dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606383103

Human homozygous R403W mutant cardiac myosin presents disproportionate enhancement of mechanical and enzymatic properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606383103

Cardiac V1 and V3 myosins differ in their hydrolytic and mechanical activities in vitro

21 January 2018

1 reference

12 December 2020

Maximal actomyosin ATPase activity and in vitro myosin motility are unaltered in human mitral regurgitation heart failure

1 reference

12 December 2020

The pathogenesis of familial hypertrophic cardiomyopathy: early and evolving effects from an alpha-cardiac myosin heavy chain missense mutation

1 reference

12 December 2020

Mutations in the motor domain modulate myosin activity and myofibril organization

1 reference

12 December 2020

Energetic aspects of muscle contraction

1 reference

12 December 2020

Smooth, cardiac and skeletal muscle myosin force and motion generation assessed by cross-bridge mechanical interactions in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0606383103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16983074%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

30 December 2019

ADS bibcode

2006PNAS..10314525S

0 references

2738193

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2738193

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16983074%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

16983074

1 reference