Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42 (Q28646556)

3 February 2017

title

Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42 (English)

1 reference

3 February 2017

1 reference

T. Reid

1

1 reference

3 February 2017

A. Bathoorn

series ordinal

2

1 reference

3 February 2017

M. R. Ahmadian

series ordinal

3

1 reference

3 February 2017

J. G. Collard

series ordinal

4

1 reference

3 February 2017

language of work or name

English

0 references

publication date

19 November 1999

1 reference

Journal of Biological Chemistry

3 February 2017

published in

1 reference

3 February 2017

volume

274

1 reference

3 February 2017

issue

47

1 reference

3 February 2017

page(s)

33587–33593

1 reference

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

3 February 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Characterization of Brx, a novel Dbl family member that modulates estrogen receptor action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

A GTP-exchange factor required for cell orientation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Expression Cloning of lfc, a Novel Oncogene with Structural Similarities to Guanine Nucleotide Exchange Factors and to the Regulatory Region of Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Structure and mutagenesis of the Dbl homology domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

The protein kinases of budding yeast: six score and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

The Eleventh Datta Lecture. The structural basis for substrate recognition and control by protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

The structure and mechanism of protein phosphatases: insights into catalysis and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Posterior end mark 2 (pem-2), pem-4, pem-5, and pem-6: maternal genes with localized mRNA in the ascidian embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Aluminum fluoride associates with the small guanine nucleotide binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

TreeView: an application to display phylogenetic trees on personal computers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Activation of the small GTPase Ral in platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

A role for Rho-like GTPases in the polarisation of mouse eight-cell blastomeres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Rho GTPases control polarity, protrusion, and adhesion during cell movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

A role for Cdc42 in macrophage chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33587

21 January 2018

Identifiers

DOI

10.1074/JBC.274.47.33587

0 references

1 reference