ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells (Q28754852)

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English	ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells	scientific article (publication date: 2 April 2009)

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title

ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells (English)

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main subject

cell biology

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author name string

Monika J Stankiewicz

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1

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John D Crispino

series ordinal

2

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language of work or name

English

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publication date

2 April 2009

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published in

Blood

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volume

113

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issue

14

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page(s)

3337-47

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limma

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Europe PubMed Central

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22 June 2022

reference URL

https://europepmc.org/article/PMC/2665899

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Ets-dependent regulation of target gene expression during megakaryopoiesis

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Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding

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Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors

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Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

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3 June 2018

Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype.

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3 June 2018

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An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

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27 November 2018

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27 November 2018

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Defective megakaryopoiesis and abnormal erythroid development in Fli-1 gene-targeted mice

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Expression of erythroid‐specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome

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High Expression Levels of theETS-Related Gene,ERG, Predict Adverse Outcome and Improve Molecular Risk-Based Classification of Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

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Identifiers

DOI

10.1182/BLOOD-2008-08-174813

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PMC publication ID

2665899

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PubMed publication ID

19168790

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ResearchGate publication ID

23939102

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