Serine/threonine-protein kinase akt-1 CELE_C12D8.10 (Q29808395)

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protein found in Caenorhabditis elegans

• akt-1
• Serine/threonine-protein kinase akt-1

edit

Language	Label	Description	Also known as
English	Serine/threonine-protein kinase akt-1 CELE_C12D8.10	protein found in Caenorhabditis elegans	akt-1 Serine/threonine-protein kinase akt-1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q17941

found in taxon

Caenorhabditis elegans

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q17941

encoded by

akt-1

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q17941

molecular function

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

protein kinase activity

determination method or standard

IDA

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

1 January 2018

stated in

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

protein serine/threonine kinase activity

determination method or standard

IDA

IEA

3 references

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

21 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

21 June 2018

stated in

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

determination method or standard

IDA

protein binding

determination method or standard

IPI

4 references

retrieved

1 January 2018

stated in

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IPI

retrieved

1 January 2018

stated in

Spindle assembly checkpoint gene mdf-1 regulates germ cell proliferation in response to nutrition signals in C. elegans

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IPI

retrieved

1 January 2018

stated in

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IPI

retrieved

1 January 2018

stated in

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IPI

calmodulin binding

determination method or standard

IDA

IEA

IPI

3 references

retrieved

1 January 2018

stated in

Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IPI

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

1 January 2018

stated in

Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

ATP binding

determination method or standard

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

phosphatidylinositol-3,4,5-trisphosphate binding

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

lipid binding

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

kinase activity

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

transferase activity

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

metal ion binding

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

protein serine/threonine kinase activity

determination method or standard

IBA

IDA

IEA

4 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

1 January 2018

stated in

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IBA

cell component

intracellular anatomical structure

determination method or standard

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

determination method or standard

IBA

cytoplasmic side of plasma membrane

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

axon

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

dendrite

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

soma

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

intracellular anatomical structure

determination method or standard

IEA

1 reference

retrieved

10 September 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

determination method or standard

IEA

biological process

immune system process

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

protein phosphorylation

determination method or standard

IDA

IEA

2 references

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

retrieved

1 January 2018

stated in

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

chemotaxis

determination method or standard

IGI

1 reference

retrieved

1 January 2018

stated in

Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IGI

multicellular organism development

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

chemosensory behavior

determination method or standard

IGI

1 reference

retrieved

1 January 2018

stated in

Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IGI

insulin receptor signaling pathway

determination method or standard

IMP

1 reference

retrieved

1 January 2018

stated in

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IMP

determination of adult lifespan

determination method or standard

IMP

1 reference

retrieved

1 January 2018

stated in

Mechanisms of life span determination in Caenorhabditis elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IMP

regulation of synaptic assembly at neuromuscular junction

determination method or standard

IGI

1 reference

retrieved

1 January 2018

stated in

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IGI

phosphorylation

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

peptidyl-serine phosphorylation

determination method or standard

IDA

1 reference

retrieved

21 June 2018

stated in

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17941&geneProductId=UniProtKB:Q17941

determination method or standard

IDA

peptidyl-threonine phosphorylation

determination method or standard

IDA

1 reference

retrieved

1 January 2018

stated in

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

determination method or standard

IMP

1 reference

retrieved

1 January 2018

stated in

AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans

GOA

curator

Community Assessment of Community Annotation with Ontologies

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IMP

innate immune response

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

response to salt

determination method or standard

IGI

1 reference

retrieved

1 January 2018

stated in

Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans

GOA

curator

UniProt

UniProt protein ID

Q17941

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IGI

protein kinase B signaling

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IEA

peptidyl-serine phosphorylation

determination method or standard

IBA

IDA

2 references

retrieved

1 January 2018

stated in

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

GOA

curator

WormBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IDA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IBA

intracellular signal transduction

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17941

determination method or standard

IBA

Identifiers

RefSeq protein ID

NP_001023645

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

179424

NP_001023646

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

179424

NP_001023647

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

179424

UniProt protein ID

Q17941

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q17941

Ensembl protein ID

C12D8.10a.1

1 reference

stated in

ensembl Release 106

Ensembl protein ID

C12D8.10a.1

C12D8.10b.1

1 reference

stated in

ensembl Release 106

Ensembl protein ID

C12D8.10b.1

C12D8.10c.1

1 reference

stated in

ensembl Release 106

Ensembl protein ID

C12D8.10c.1

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q29808395&oldid=2211950156"