TNF-receptor-associated factor 6 Dmel_CG10961 (Q29809838)

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Protein found in Drosophila melanogaster

• EP325
• CG10961-PA
• CG10961 gene product from transcript CG10961-RA
• tumor necrosis factor receptor 2
• TNF-receptor-associated factor 2
• Traf6-PA
• Traf6
• TNF-receptor-associated factor 6

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Language	Label	Description	Also known as
English	TNF-receptor-associated factor 6 Dmel_CG10961	Protein found in Drosophila melanogaster	EP325 CG10961-PA CG10961 gene product from transcript CG10961-RA tumor necrosis factor receptor 2 TNF-receptor-associated factor 2 Traf6-PA Traf6 TNF-receptor-associated factor 6

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9W3I9

part of

TRAF-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

Zinc finger, RING/FYVE/PHD-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

TNF receptor-associated factor 6

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

MATH/TRAF domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

TNF receptor-associated factor 6, MATH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9W3I9

encoded by

Traf6

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9W3I9

molecular function

ubiquitin-protein transferase activity

determination method or standard

IEA

ISS

2 references

retrieved

16 July 2018

stated in

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3I9&geneProductId=UniProtKB:Q9W3I9

determination method or standard

ISS

retrieved

16 July 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3I9&geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

tumor necrosis factor receptor binding

determination method or standard

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3I9&geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

protein binding

determination method or standard

IPI

3 references

retrieved

8 April 2019

stated in

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily

GOA

curator

UniProt

UniProt protein ID

Q9W3I9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IPI

retrieved

8 April 2019

stated in

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IPI

retrieved

8 April 2019

stated in

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IPI

zinc ion binding

determination method or standard

ISM

1 reference

retrieved

8 April 2019

stated in

Comprehensively surveying structure and function of RING domains from Drosophila melanogaster

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

ISM

metal ion binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9W3I9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

ubiquitin-protein transferase activity

determination method or standard

IBA

IEA

ISS

3 references

retrieved

8 April 2019

stated in

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IBA

tumor necrosis factor receptor binding

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IBA

cell component

cytoplasm

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

ISS

protein-containing complex

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IBA

biological process

protein polyubiquitination

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

ISS

dorsal closure

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Roles of the JNK signaling pathway in Drosophila morphogenesis.

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

TAS

Toll signaling pathway

determination method or standard

TAS

1 reference

retrieved

7 November 2018

stated in

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3I9&geneProductId=UniProtKB:Q9W3I9

determination method or standard

TAS

cell death

determination method or standard

IGI

1 reference

retrieved

8 April 2019

stated in

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IGI

positive regulation of autophagy

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IMP

protein ubiquitination

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

stress-activated protein kinase signaling cascade

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IMP

regulation of I-kappaB kinase/NF-kappaB signaling

determination method or standard

IEA

IMP

2 references

retrieved

8 April 2019

stated in

Discrete Functions of TRAF1 and TRAF2 in Drosophila melanogaster Mediated by c-Jun N-Terminal Kinase and NF-κB-Dependent Signaling Pathways

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IEA

innate immune response

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Discrete Functions of TRAF1 and TRAF2 in Drosophila melanogaster Mediated by c-Jun N-Terminal Kinase and NF-κB-Dependent Signaling Pathways

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IMP

negative regulation of Notch signaling pathway

determination method or standard

IGI

IPI

2 references

retrieved

8 April 2019

stated in

TRAF6 is a novel regulator of Notch signaling in Drosophila melanogaster

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IPI

retrieved

8 April 2019

stated in

TRAF6 is a novel regulator of Notch signaling in Drosophila melanogaster

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IGI

regulation of defense response to virus

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IMP

defense response to Gram-negative bacterium

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IMP

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IBA

positive regulation of NF-kappaB transcription factor activity

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IBA

protein K63-linked ubiquitination

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method or standard

IBA

has part(s)

MATH/TRAF domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

Zinc finger, RING-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

Zinc finger, RING-type, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

TNF receptor-associated factor 6, MATH domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

Identifiers

RefSeq protein ID

NP_511080

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

31746

UniProt protein ID

Q9W3I9

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9W3I9

Ensembl protein ID

FBpp0071136

1 reference

stated in

ensembl Release 106

Ensembl protein ID

FBpp0071136

 

Sitelinks

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q29809838&oldid=2030255119"