Sex-determining transformer protein 1 CELE_Y47D3A.6 (Q29801205)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34708

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

23 May 2018

1 reference

23 May 2018

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

1 January 2018

TRA-1A regulates transcription of fog-3, which controls germ cell fate in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

RNA polymerase II cis-regulatory region sequence-specific DNA binding

RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

1 reference

1 January 2018

Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 reference

1 January 2018

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 reference

1 January 2018

protein binding

1 reference

1 January 2018

Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

protein C-terminus binding

1 reference

1 January 2018

The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

sequence-specific DNA binding

1 reference

1 January 2018

Zinc fingers in sex determination: only one of the two C. elegans Tra-1 proteins binds DNA in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 reference

1 January 2018

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

5 references

16 July 2018

16 July 2018

The C. elegans sex-determining GLI protein TRA-1A is regulated by sex-specific proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

16 July 2018

RNA-Regulated TRA-1 nuclear export controls sexual fate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

16 July 2018

MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

16 July 2018

RNA-Regulated TRA-1 nuclear export controls sexual fate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

3 references

1 January 2018

1 January 2018

RNA-Regulated TRA-1 nuclear export controls sexual fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 January 2018

RNA-Regulated TRA-1 nuclear export controls sexual fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

6 references

1 January 2018

1 January 2018

MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 January 2018

RNA-Regulated TRA-1 nuclear export controls sexual fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 January 2018

The C. elegans sex-determining GLI protein TRA-1A is regulated by sex-specific proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 January 2018

RNA-Regulated TRA-1 nuclear export controls sexual fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

negative regulation of transcription by RNA polymerase II

biological process

1 reference

1 January 2018

TRA-1A regulates transcription of fog-3, which controls germ cell fate in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34708&geneProductId=UniProtKB:P34708

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 reference

1 January 2018

sex differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 reference

1 January 2018

female germ-line sex determination

TAS

1 reference

1 January 2018

The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

female somatic sex determination

TAS

Molecular analysis of the C. elegans sex-determining gene tra-1: a gene encoding two zinc finger proteins

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

TAS

1 January 2018

The tra-1 gene determines sexual phenotype cell-autonomously in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 January 2018

A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

1 reference

1 January 2018

positive regulation of neuron apoptotic process

1 reference

1 January 2018

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

regulation of transcription by RNA polymerase II

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

central nervous system development

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34708

has part(s)

Zinc finger C2H2-type

1 reference

InterPro Release 71.0