Fused Dmel_CG6551 (Q29815568)

From Wikidata
Jump to navigation Jump to search
Protein found in Drosophila melanogaster
  • CG6551-PA
  • CG6551 gene product from transcript CG6551-RA
  • fu
  • fu-PA
  • fused
edit
Language Label Description Also known as
English
Fused Dmel_CG6551
Protein found in Drosophila melanogaster
  • CG6551-PA
  • CG6551 gene product from transcript CG6551-RA
  • fu
  • fu-PA
  • fused

Statements

molecular function
protein binding
determination method or standard
IPI
8 references
retrieved
9 May 2019
stated in
The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
The sex determination master switch, Sex-lethal, responds to Hedgehog signaling in the Drosophila germline.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
A positive role for Patched in Hedgehog signaling revealed by the intracellular trafficking of Sex-lethal, the Drosophila sex determination master switch
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
retrieved
9 May 2019
stated in
The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IPI
cell component
biological process
smoothened signaling pathway
determination method or standard
IGI
IMP
10 references
retrieved
7 November 2018
stated in
Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
Nuclear import of cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
7 November 2018
stated in
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23647&geneProductId=UniProtKB:P23647
determination method or standard
IGI
smoothened signaling pathway
determination method or standard
IDA
IGI
IMP
11 references
retrieved
9 May 2019
stated in
Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
Nuclear import of cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IMP
retrieved
9 May 2019
stated in
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IGI
retrieved
9 May 2019
stated in
The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23647
determination method or standard
IDA

Identifiers

 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q29815568&oldid=2030282695"