Actin-related protein 2/3 complex, subunit 1 Dmel_CG8978 (Q29817903)

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Protein found in Drosophila melanogaster

• CG8978 gene product from transcript CG8978-RB
• profilin 2
• CG8978-PB
• lethal(2)34Dd
• Actin-related protein 2/3 complex, subunit 1
• CG8978-PA
• suppressor of
• Arpc1
• Arpc1-PA
• Arpc1-PB
• suppressor of profilin 2

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Language	Label	Description	Also known as
English	Actin-related protein 2/3 complex, subunit 1 Dmel_CG8978	Protein found in Drosophila melanogaster	CG8978 gene product from transcript CG8978-RB profilin 2 CG8978-PB lethal(2)34Dd Actin-related protein 2/3 complex, subunit 1 CG8978-PA suppressor of Arpc1 Arpc1-PA Arpc1-PB suppressor of profilin 2

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O97182

part of

WD40/YVTN repeat-like-containing domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O97182

WD40-repeat-containing domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O97182

Actin-related protein 2/3 complex subunit 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O97182

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O97182

encoded by

Arpc1

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O97182

molecular function

actin binding

determination method or standard

IEA

ISS

2 references

retrieved

8 April 2019

stated in

Flying through the drosophila cytoskeletal genome.

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O97182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

structural constituent of cytoskeleton

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

ISS

actin filament binding

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IBA

cell component

cytoplasm

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O97182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

cytoskeleton

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O97182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

arp2/3 protein complex

determination method or standard

IEA

ISS

NAS

TAS

5 references

retrieved

31 January 2018

stated in

Orc mutants arrest in metaphase with abnormally condensed chromosomes.

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

TAS

retrieved

31 January 2018

stated in

The WASP-Arp2/3 pathway: genetic insights

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

NAS

retrieved

31 January 2018

stated in

A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

ISS

retrieved

31 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O97182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

IEA

retrieved

31 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

IEA

actin cytoskeleton

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

arp2/3 protein complex

determination method or standard

IBA

IEA

ISS

NAS

TAS

6 references

retrieved

8 April 2019

stated in

Orc mutants arrest in metaphase with abnormally condensed chromosomes.

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

TAS

retrieved

8 April 2019

stated in

The WASP-Arp2/3 pathway: genetic insights

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

NAS

retrieved

8 April 2019

stated in

A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O97182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IBA

biological process

cell morphogenesis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

compound eye morphogenesis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

intracellular protein transport

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

axonogenesis

determination method or standard

IGI

1 reference

retrieved

8 April 2019

stated in

SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IGI

axonal fasciculation

determination method or standard

IGI

1 reference

retrieved

8 April 2019

stated in

SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IGI

chaeta morphogenesis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

chaeta development

determination method or standard

IMP

1 reference

retrieved

10 September 2018

stated in

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

IMP

actin filament-based process

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

actin filament reorganization involved in cell cycle

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

pseudocleavage involved in syncytial blastoderm formation

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

regulation of actin filament polymerization

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

cell adhesion mediated by integrin

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

WAVE Forms Hetero- and Homo-oligomeric Complexes at Integrin Junctions in Drosophila Visualized by Bimolecular Fluorescence Complementation

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

Arp2/3 complex-mediated actin nucleation

determination method or standard

IBA

IEA

ISS

4 references

retrieved

8 April 2019

stated in

A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O97182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IBA

positive regulation of Notch signaling pathway

determination method or standard

IMP

1 reference

retrieved

10 September 2018

stated in

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O97182&geneProductId=UniProtKB:O97182

determination method or standard

IMP

positive regulation of filopodium assembly

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O97182

determination method or standard

IMP

has part(s)

WD40 repeat

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O97182

Identifiers

RefSeq protein ID

NP_476596

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

34793

NP_723845

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

34793

UniProt protein ID

O97182

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O97182

Ensembl protein ID

FBpp0080146

1 reference

stated in

ensembl Release 106

Ensembl protein ID

FBpp0080146

FBpp0080147

1 reference

stated in

ensembl Release 106

Ensembl protein ID

FBpp0080147

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q29817903&oldid=2030296084"