Basket Dmel_CG5680 (Q29819549)

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Protein found in Drosophila melanogaster

Jun NH2-terminal kinase
Jun N-terminal kinase
bsk-PB
CG5680 gene product from transcript CG5680-RB
Jun-N-terminal kinase
Jun-N terminal kinase
bsk-PE
pJNK
CG5680-PE
bsk-PF
CG5680-PF
c-Jun N-terminal kinase
basket
JUN kinase
Jun-kinase
c-Jun aminoterminal kinase
c-Jun-N-terminal kinase
CG5680-PB
bsk
JNK

Language	Label	Description	Also known as
English	Basket Dmel_CG5680	Protein found in Drosophila melanogaster	Jun NH2-terminal kinase Jun N-terminal kinase bsk-PB CG5680 gene product from transcript CG5680-RB Jun-N-terminal kinase Jun-N terminal kinase bsk-PE pJNK CG5680-PE bsk-PF CG5680-PF c-Jun N-terminal kinase basket JUN kinase Jun-kinase c-Jun aminoterminal kinase c-Jun-N-terminal kinase CG5680-PB bsk JNK

Statements

1 reference

25 May 2022

UniProt protein ID

mitogen-activated protein (MAP) kinase, JNK

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P92208

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P92208

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Mitogen-activated protein (MAP) kinase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

protein serine/threonine kinase activity

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

kinase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

JUN kinase activity

determination method or standard

6 references

27 February 2018

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

p38 MAPK signalling cascades: ancient roles and new functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

The Drosophila cell shape regulator c-Jun N-terminal kinase also functions as a stress-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

JUN kinase activity

determination method or standard

7 references

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

p38 MAPK signalling cascades: ancient roles and new functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

The Drosophila cell shape regulator c-Jun N-terminal kinase also functions as a stress-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

MAP kinase activity

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

1 reference

8 April 2019

Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

biological process

determination method or standard

1 reference

8 April 2019

p38 MAPK signalling cascades: ancient roles and new functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

establishment of planar polarity

determination method or standard

1 reference

8 April 2019

Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

protein phosphorylation

determination method or standard

3 references

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

response to oxidative stress

determination method or standard

1 reference

8 April 2019

JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

4 references

27 February 2018

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

27 February 2018

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

JUN phosphorylation

determination method or standard

1 reference

8 April 2019

The Drosophila cell shape regulator c-Jun N-terminal kinase also functions as a stress-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

multicellular organism development

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

border follicle cell migration

determination method or standard

1 reference

27 February 2018

A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

dorsal closure, spreading of leading edge cells

determination method or standard

1 reference

8 April 2019

Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

long-term memory

determination method or standard

1 reference

8 April 2019

A permissive role of mushroom body α/β core neurons in long-term memory consolidation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

cellular response to starvation

determination method or standard

1 reference

8 April 2019

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

response to heat

determination method or standard

1 reference

8 April 2019

JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

regulation of gene expression

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

positive regulation of autophagy

determination method or standard

1 reference

8 April 2019

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

positive regulation of gene expression

determination method or standard

1 reference

8 April 2019

Scarface, a secreted serine protease-like protein, regulates polarized localization of laminin A at the basement membrane of the Drosophila embryo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

phosphorylation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

mushroom body development

determination method or standard

1 reference

8 April 2019

Developmental Axon Pruning Requires Destabilization of Cell Adhesion by JNK Signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

antibacterial humoral response

determination method or standard

1 reference

8 April 2019

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

ovarian follicle cell development

determination method or standard

1 reference

8 April 2019

Notch signaling through tramtrack bypasses the mitosis promoting activity of the JNK pathway in the mitotic-to-endocycle transition of Drosophila follicle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

cellular response to oxidative stress

determination method or standard

1 reference

8 April 2019

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

cellular response to reactive oxygen species

determination method or standard

1 reference

8 April 2019

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

melanization defense response

determination method or standard

wound healing, spreading of epidermal cells

determination method or standard

1 reference

8 April 2019

Cellular and genetic analysis of wound healing in Drosophila larvae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

negative regulation of JUN kinase activity

determination method or standard

1 reference

8 April 2019

Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

engulfment of apoptotic cell

determination method or standard

1 reference

8 April 2019

Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

imaginal disc fusion, thorax closure

determination method or standard

dorsal appendage formation

determination method or standard

1 reference

8 April 2019

The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

chorion micropyle formation

determination method or standard

1 reference

8 April 2019

The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

embryonic anterior midgut (ectodermal) morphogenesis

determination method or standard

1 reference

8 April 2019

D-JNK signaling in visceral muscle cells controls the laterality of the Drosophila gut.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

neuron development

determination method or standard

1 reference

8 April 2019

Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

collateral sprouting of injured axon

determination method or standard

1 reference

8 April 2019

Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

1 reference

8 April 2019

A signaling network for patterning of neuronal connectivity in the Drosophila brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

imaginal disc-derived male genitalia morphogenesis

determination method or standard

1 reference

8 April 2019

Apoptosis controls the speed of looping morphogenesis in Drosophila male terminalia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

neuron projection morphogenesis

determination method or standard

1 reference

8 April 2019

Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

cellular response to arsenic-containing substance

determination method or standard

1 reference

8 April 2019

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

cellular response to cadmium ion

determination method or standard

1 reference

8 April 2019

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination of digestive tract left/right asymmetry

determination method or standard

1 reference

8 April 2019

D-JNK signaling in visceral muscle cells controls the laterality of the Drosophila gut.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

positive regulation of border follicle cell migration

determination method or standard

1 reference

27 February 2018

Regulation of cell adhesion and collective cell migration by hindsight and its human homolog RREB1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P92208&geneProductId=UniProtKB:P92208

determination method or standard

positive regulation of neuron remodeling

determination method or standard

1 reference

8 April 2019

Developmental Axon Pruning Requires Destabilization of Cell Adhesion by JNK Signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

4 references

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

determination method or standard

5 references

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

intracellular signal transduction

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

cellular response to organic substance

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

positive regulation of border follicle cell migration

determination method or standard

vascular endothelial growth factor receptor signaling pathway

determination method or standard

1 reference

8 April 2019

PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P92208

determination method or standard

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P92208

mitogen-activated protein (MAP) kinase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P92208

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P92208

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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