Wingless Dmel_CG4889 (Q29812690)

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Protein found in Drosophila melanogaster
  • bristled
  • spade
  • Wnt-1
  • beta-Catenin
  • glazed
  • CG4889-PA
  • CG4889 gene product from transcript CG4889-RA
  • wg-PA
  • sternopleural
  • wingless
  • lethal (2) SH1281
  • flag
  • Wg
  • complementation group I
edit
Language Label Description Also known as
English
Wingless Dmel_CG4889
Protein found in Drosophila melanogaster
  • bristled
  • spade
  • Wnt-1
  • beta-Catenin
  • glazed
  • CG4889-PA
  • CG4889 gene product from transcript CG4889-RA
  • wg-PA
  • sternopleural
  • wingless
  • lethal (2) SH1281
  • flag
  • Wg
  • complementation group I

Statements

molecular function
protein binding
determination method or standard
IPI
5 references
retrieved
8 April 2019
stated in
Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum
GOA
curator
UniProt
UniProt protein ID
P09615
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IPI
retrieved
8 April 2019
stated in
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex
GOA
curator
UniProt
UniProt protein ID
P09615
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IPI
retrieved
8 April 2019
stated in
Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling
GOA
curator
UniProt
UniProt protein ID
P09615
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IPI
retrieved
8 April 2019
stated in
p24 proteins are required for secretion of Wnt ligands
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IPI
retrieved
8 April 2019
stated in
Roles of N-glycosylation and lipidation in Wg secretion and signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IPI
cell component
extracellular space
determination method or standard
IBA
IDA
9 references
retrieved
24 April 2018
stated in
Sulfated is a negative feedback regulator of wingless in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
Carrier of Wingless (Cow), a secreted heparan sulfate proteoglycan, promotes extracellular transport of Wingless.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615
determination method or standard
IBA
extracellular space
determination method or standard
IDA
8 references
retrieved
8 April 2019
stated in
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Carrier of Wingless (Cow), a secreted heparan sulfate proteoglycan, promotes extracellular transport of Wingless.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Sulfated is a negative feedback regulator of wingless in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
biological process
canonical Wnt signaling pathway
determination method or standard
IDA
IGI
IMP
12 references
retrieved
8 April 2019
stated in
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IMP
retrieved
8 April 2019
stated in
The wingless signalling pathway and the patterning of the wing margin in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IMP
retrieved
8 April 2019
stated in
A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IMP
retrieved
8 April 2019
stated in
The wingless signaling pathway is directly involved in Drosophila heart development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IMP
retrieved
8 April 2019
stated in
Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IMP
retrieved
8 April 2019
stated in
Porcupine-mediated lipidation is required for Wnt recognition by Wls.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IMP
retrieved
8 April 2019
stated in
The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IGI
retrieved
8 April 2019
stated in
Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
A new member of the frizzled family from Drosophila functions as a Wingless receptor
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA
retrieved
8 April 2019
stated in
Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615
determination method or standard
IDA

Identifiers

 
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