A-kinase anchoring protein 6 (Q21108172)

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mammalian protein found in Homo sapiens

Protein kinase A-anchoring protein 6
AKAP6
PRKA6
AKAP 100
protein kinase A anchoring protein 6
AKAP-6
A-kinase anchor protein 100 kDa
A kinase (PRKA) anchor protein 6
mAKAP
A-kinase anchor protein 6

Language	Label	Description	Also known as
English	A-kinase anchoring protein 6	mammalian protein found in Homo sapiens	Protein kinase A-anchoring protein 6 AKAP6 PRKA6 AKAP 100 protein kinase A anchoring protein 6 AKAP-6 A-kinase anchor protein 100 kDa A kinase (PRKA) anchor protein 6 mAKAP A-kinase anchor protein 6

Statements

1 reference

13 November 2019

UniProt protein ID

Spectrin/alpha-actinin, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein-membrane adaptor activity

determination method or standard

1 reference

8 April 2019

mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

transmembrane transporter binding

determination method or standard

1 reference

16 July 2018

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

protein kinase A binding

determination method or standard

protein binding

determination method or standard

2 references

protein kinase A regulatory subunit binding

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

adenylate cyclase binding

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

transmembrane transporter binding

determination method or standard

protein kinase A binding

determination method or standard

3 references

8 April 2019

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

nuclear envelope

determination method or standard

1 reference

8 April 2019

mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

calcium channel complex

determination method or standard

1 reference

8 April 2019

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

intercalated disc

determination method or standard

1 reference

8 April 2019

A-kinase anchoring protein 100 (AKAP100) is localized in multiple subcellular compartments in the adult rat heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

determination method or standard

1 reference

8 April 2019

A-kinase anchoring protein 100 (AKAP100) is localized in multiple subcellular compartments in the adult rat heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

junctional sarcoplasmic reticulum membrane

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

sarcoplasmic reticulum

determination method or standard

3 references

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

16 July 2018

Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

16 July 2018

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

perinuclear region of cytoplasm

determination method or standard

3 references

16 July 2018

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

16 July 2018

mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

sarcoplasmic reticulum

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

perinuclear region of cytoplasm

determination method or standard

4 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

biological process

protein targeting

determination method or standard

positive regulation of release of sequestered calcium ion into cytosol

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

regulation of protein kinase A signaling

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

cellular response to cytokine stimulus

determination method or standard

1 reference

8 April 2019

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of delayed rectifier potassium channel activity

determination method or standard

1 reference

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of ryanodine-sensitive calcium-release channel activity

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of calcineurin-NFAT signaling cascade

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of cell growth

determination method or standard

1 reference

8 April 2019

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of potassium ion transmembrane transport

determination method or standard

1 reference

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

action potential

determination method or standard

1 reference

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

regulation of membrane repolarization

determination method or standard

1 reference

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of cell growth involved in cardiac muscle cell development

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

cAMP-mediated signaling

determination method or standard

1 reference

8 April 2019

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

cellular response to cAMP

determination method or standard

1 reference

8 April 2019

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13023

determination method or standard

positive regulation of phosphoprotein phosphatase activity

determination method or standard

1 reference

7 November 2018

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

intracellular signal transduction

determination method or standard

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13023&geneProductId=UniProtKB:Q13023

determination method or standard

Spectrin/alpha-actinin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13023

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000280979

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000280979

ENSP00000450531

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000450531

ENSP00000451146

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000451146

ENSP00000451239

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000451239

ENSP00000451246

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000451246

ENSP00000451247

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000451247

ENSP00000452109

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452109

ENSP00000452204

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452204

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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