Replication protein A1 (Q21109589)

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mammalian protein found in Homo sapiens
  • RPA1
  • MSTP075
  • replication protein A1, 70kDa
  • single-stranded DNA-binding protein
  • replication factor A protein 1
  • replication protein A 70 kDa DNA-binding subunit
  • RF-A protein 1
  • RP-A p70
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Language Label Description Also known as
English
Replication protein A1
mammalian protein found in Homo sapiens
  • RPA1
  • MSTP075
  • replication protein A1, 70kDa
  • single-stranded DNA-binding protein
  • replication factor A protein 1
  • replication protein A 70 kDa DNA-binding subunit
  • RF-A protein 1
  • RP-A p70

Statements

molecular function
protein binding
determination method
IPI
21 references
retrieved
8 April 2019
stated in
Activation of the ATR kinase by the RPA-binding protein ETAA1
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
RPA involvement in the damage-recognition and incision steps of nucleotide excision repair
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
SLFN11 Blocks Stressed Replication Forks Independently of ATR.
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of DNA polymerase alpha-primase with cellular replication protein A and SV40 T antigen
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
ETAA1 acts at stalled replication forks to maintain genome integrity
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Functional and physical interaction between WRN helicase and human replication protein A
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Timed interactions between viral and cellular replication factors during the initiation of SV40 in vitro DNA replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Different activities of the largest subunit of replication protein A cooperate during SV40 DNA replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
p53 modulates RPA-dependent and RPA-independent WRN helicase activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
cell component
DNA replication factor A complex
determination method
IBA
IDA
IEA
IPI
6 references
retrieved
8 April 2019
stated in
Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IPI
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IEA
retrieved
8 April 2019
stated in
Activation of the ATR kinase by the RPA-binding protein ETAA1
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IDA
retrieved
8 April 2019
stated in
ETAA1 acts at stalled replication forks to maintain genome integrity
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IDA
retrieved
8 April 2019
stated in
Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA
GOA
curator
UniProt
UniProt protein ID
P27694
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694
determination method
IBA
biological process

Identifiers

PDB structure ID
 
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