Chromodomain helicase DNA binding protein 3 (Q21100363)

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mammalian protein found in Homo sapiens

ATP-dependent helicase CHD3
CHD3
chromodomain-helicase-DNA-binding protein 3
zinc-finger helicase (Snf2-like)
mi-2 autoantigen 240 kDa protein
CHD-3
zinc finger helicase
Mi2-alpha
hZFH

Language	Label	Description	Also known as
English	Chromodomain helicase DNA binding protein 3	mammalian protein found in Homo sapiens	ATP-dependent helicase CHD3 CHD3 chromodomain-helicase-DNA-binding protein 3 zinc-finger helicase (Snf2-like) mi-2 autoantigen 240 kDa protein CHD-3 zinc finger helicase Mi2-alpha hZFH

Statements

1 reference

13 November 2019

UniProt protein ID

Zinc finger, FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Chromo-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Zinc finger, RING/FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

High mobility group box domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

SNF2-like, N-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Chromo domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-finger, protein family

1 reference

based on heuristic

inferred from protein domain or family

Domain of unknown function DUF1086, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

CHD, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SNF2-related, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Chromo/chromo shadow domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CHD, C-terminal 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

Chromo domain, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Domain of unknown function DUF1087, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

DNA helicase activity

determination method or standard

1 reference

8 April 2019

Characterization of the CHD family of proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

hydrolase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

protein binding

determination method or standard

10 references

8 April 2019

PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

A human protein-protein interaction network: a resource for annotating the proteome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

A directed protein interaction network for investigating intracellular signal transduction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Phosphorylated p68 RNA helicase activates snail1 transcription by promoting HDAC1 dissociation from the snail1 promoter

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

histone deacetylase activity

determination method or standard

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12873&geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

1 reference

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12873&geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

1 reference

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

ATPase activity

determination method or standard

1 reference

8 April 2019

CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

double-stranded DNA helicase activity

determination method or standard

1 reference

8 April 2019

CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

4 references

8 April 2019

Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

8 April 2019

Differential distribution of unmodified and phosphorylated histone deacetylase 2 in chromatin

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

1 reference

8 April 2019

Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

biological process

transcription, DNA-templated

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12873&geneProductId=UniProtKB:Q12873

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Characterization of the CHD family of proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

histone deacetylation

determination method or standard

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12873&geneProductId=UniProtKB:Q12873

determination method or standard

DNA duplex unwinding

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

regulation of signal transduction by p53 class mediator

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12873

determination method or standard

Domain of unknown function DUF1087

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Domain of unknown function DUF1086

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Chromo domain, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Zinc finger, PHD-type, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Helicase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

CHD, C-terminal 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Chromo/chromo shadow domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

SNF2-related, N-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Zinc finger, PHD-finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

CHD, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Helicase superfamily 1/2, ATP-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Zinc finger, PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12873

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000332628

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000332628

ENSP00000350907

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000350907

ENSP00000369716

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000369716

ENSP00000395252

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395252

ENSP00000405861

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405861

ENSP00000411959

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411959

ENSP00000458861

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458861

ENSP00000459321

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000459321

ENSP00000467547

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467547

ENSP00000500513

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000500513

ENSP00000500734

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000500734

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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