Protein tyrosine phosphatase non-receptor type 4 (Q21102512)

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mammalian protein found in Homo sapiens

• PTPase-MEG1
• PTPN4
• megakaryocyte phosphatase
• Protein-tyrosine phosphatase MEG1
• protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
• tyrosine-protein phosphatase non-receptor type 4
• megakaryocyte protein-tyrosine phosphatase
• MEG
• protein tyrosine phosphatase MEG1

edit

Language	Label	Description	Also known as
English	Protein tyrosine phosphatase non-receptor type 4	mammalian protein found in Homo sapiens	PTPase-MEG1 PTPN4 megakaryocyte phosphatase Protein-tyrosine phosphatase MEG1 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) tyrosine-protein phosphatase non-receptor type 4 megakaryocyte protein-tyrosine phosphatase MEG protein tyrosine phosphatase MEG1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P29074

part of

Ubiquitin-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Protein-tyrosine phosphatase-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM superfamily, second domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM/acyl-CoA-binding protein superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

PDZ superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Protein-tyrosine phosphatase, non-receptor type-3, -4

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

PH-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Band 4.1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, C-terminal PH-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PTP type protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM adjacent (FA), protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PDZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P29074

encoded by

PTPN4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P29074

molecular function

protein tyrosine phosphatase activity

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

phosphatase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

cytoskeletal protein binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

protein binding

determination method or standard

IPI

4 references

retrieved

8 April 2019

stated in

A human protein-protein interaction network: a resource for annotating the proteome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IPI

retrieved

8 April 2019

stated in

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IPI

retrieved

8 April 2019

stated in

Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IPI

retrieved

8 April 2019

stated in

Toward an understanding of the protein interaction network of the human liver

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IPI

phosphoprotein phosphatase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

hydrolase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

non-membrane spanning protein tyrosine phosphatase activity

determination method or standard

IEA

TAS

2 references

retrieved

8 April 2019

stated in

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

cell component

cytoplasm

determination method or standard

IDA

IEA

TAS

3 references

retrieved

8 April 2019

stated in

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

retrieved

8 April 2019

stated in

Subcellular localization of intracellular protein tyrosine phosphatases in T cells

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IDA

cytoplasmic side of plasma membrane

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Subcellular localization of intracellular protein tyrosine phosphatases in T cells

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IDA

plasma membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

cytoskeleton

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P29074

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

nucleoplasm

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

TAS

cytosol

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

TAS

biological process

protein dephosphorylation

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

peptidyl-tyrosine dephosphorylation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

dephosphorylation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

IEA

cellular response to cytokine stimulus

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29074

determination method or standard

TAS

has part(s)

PDZ domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Tyrosine specific protein phosphatases domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM adjacent (FA)

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM, C-terminal PH-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Band 4.1 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM central domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Protein-tyrosine phosphatase, active site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

PTP type protein phosphatase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

FERM domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Protein-tyrosine phosphatase, catalytic

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P29074

Identifiers

MeSH descriptor ID

D054590

subject named as

Protein Tyrosine Phosphatase, Non-Receptor Type 4

0 references

MeSH tree code

D08.811.277.352.650.775.300.400

0 references

D12.776.476.564.300.400

0 references

RefSeq protein ID

NP_002821

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5775

UniProt protein ID

P29074

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P29074

Ensembl protein ID

ENSP00000263708

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000263708

ENSP00000387457

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000387457

ENSP00000394706

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000394706

ENSP00000395603

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000395603

ENSP00000405763

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000405763

ENSP00000411364

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000411364

ENSP00000438445

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000438445

PDB structure ID

2CS5

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

2VPH

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

3NFK

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

3NFL

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

2I75

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

5EZ0

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

5EYZ

1 reference

stated in

UniProt

UniProt protein ID

P29074

retrieved

9 August 2016

language of work or name

English

UMLS CUI

C0666228

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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