Cell death inducing DFFA like effector a (Q21115661)

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mammalian protein found in Homo sapiens

• Cell death-inducing DFFA-like effector A
• cell death activator CIDE-A
• CIDEA

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Language	Label	Description	Also known as
English	Cell death inducing DFFA like effector a	mammalian protein found in Homo sapiens	Cell death-inducing DFFA-like effector A cell death activator CIDE-A CIDEA

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O60543

part of

Cell death activator CIDE-A

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O60543

CIDE-N domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O60543

encoded by

CIDEA

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O60543

molecular function

protein homodimerization activity

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

cell component

cytoplasm

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

lipid droplet

determination method or standard

IDA

IEA

4 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O60543

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

27 March 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

27 March 2018

stated in

Cidea is associated with lipid droplets and insulin sensitivity in humans

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IDA

intracellular anatomical structure

determination method or standard

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IEA

mitochondrion

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

mitochondrial envelope

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

nucleus

determination method or standard

ISS

IEA

3 references

retrieved

8 April 2019

stated in

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O60543

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

cytosol

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

TAS

lipid droplet

determination method or standard

IBA

IDA

IEA

5 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O60543

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

8 April 2019

stated in

Cidea is associated with lipid droplets and insulin sensitivity in humans

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IBA

biological process

regulation of apoptotic process

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IBA

negative regulation of execution phase of apoptosis

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O60543

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IEA

lipid metabolism

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

lipid storage

determination method or standard

ISS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

cell death

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

negative regulation of transforming growth factor beta receptor signaling pathway

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O60543

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60543&geneProductId=UniProtKB:O60543

determination method or standard

IEA

positive regulation of sequestering of triglyceride

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

Cidea is associated with lipid droplets and insulin sensitivity in humans

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

response to stilbenoid

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

negative regulation of tumor necrosis factor production

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IMP

temperature homeostasis

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

negative regulation of lipid catabolic process

determination method or standard

ISS

IEA

IMP

3 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

regulation of apoptotic DNA fragmentation

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

apoptotic process

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O60543

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

lipid droplet organization

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

TAS

negative regulation of cold-induced thermogenesis

determination method or standard

IEA

ISS

2 references

retrieved

8 April 2019

stated in

Cidea-deficient mice have lean phenotype and are resistant to obesity

GOA

curator

YuBioLab

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60543

determination method or standard

IEA

has part(s)

CIDE-N domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O60543

Identifiers

RefSeq protein ID

NP_001270

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1149

NP_001305312

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1149

UniProt protein ID

O60543

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O60543

Ensembl protein ID

ENSP00000320209

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000320209

ENSP00000429238

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000429238

PDB structure ID

2EEL

1 reference

stated in

UniProt

UniProt protein ID

O60543

retrieved

21 March 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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