Calcium and integrin binding 1 (Q21115672)

http://www.ebi.ac.uk/interpro/protein/Q99828

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EF-Hand 1, calcium-binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein serine/threonine kinase inhibitor activity

1 reference

8 April 2019

Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

transmembrane transporter binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

protein C-terminus binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

protein binding

12 references

8 April 2019

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Wiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesion

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

CIB1 is a regulator of pathological cardiac hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

calcium-dependent protein kinase inhibitor activity

1 reference

8 April 2019

Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

cell component

cytoplasm

A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

CIB1 is a regulator of pathological cardiac hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

vesicle

1 reference

17 October 2017

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99828&geneProductId=UniProtKB:Q99828

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

centrosome

1 reference

8 April 2019

Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

4 references

8 April 2019

8 April 2019

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

8 April 2019

Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

ruffle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

axon

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

dendrite

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

apical plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

endoplasmic reticulum

1 reference

8 April 2019

A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

neuron projection

1 reference

8 April 2019

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

sarcolemma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

CIB1 is a regulator of pathological cardiac hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

extracellular exosome

4 references

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99828&geneProductId=UniProtKB:Q99828

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99828&geneProductId=UniProtKB:Q99828

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99828&geneProductId=UniProtKB:Q99828

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99828&geneProductId=UniProtKB:Q99828

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

cell periphery

2 references

8 April 2019

The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

vesicle

1 reference

8 April 2019

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

extracellular exosome

3 references

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

positive regulation of protein targeting to membrane

biological process

1 reference

8 April 2019

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

cellular response to nerve growth factor stimulus

1 reference

8 April 2019

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

negative regulation of neuron projection development

1 reference

8 April 2019

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

regulation of cell division

1 reference

8 April 2019

Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

extrinsic apoptotic signaling pathway

1 reference

8 April 2019

CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

cellular response to tumor necrosis factor

1 reference

8 April 2019

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

cellular response to DNA damage stimulus

1 reference

8 April 2019

EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

negative regulation of microtubule depolymerization

1 reference

8 April 2019

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

positive regulation of substrate adhesion-dependent cell spreading

1 reference

8 April 2019

The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

regulation of cell population proliferation

1 reference

8 April 2019

Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

positive regulation of NF-kappaB transcription factor activity

1 reference

8 April 2019

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

double-strand break repair

1 reference

8 April 2019

Interaction between DNA-dependent protein kinase and a novel protein, KIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

cytoplasmic microtubule organization

1 reference

8 April 2019

Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

endomitotic cell cycle

1 reference

8 April 2019

Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

8 April 2019

positive regulation of cell adhesion mediated by integrin

1 reference

8 April 2019

The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

negative regulation of cell population proliferation

1 reference

8 April 2019

Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

negative regulation of protein kinase activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

negative regulation of protein serine/threonine kinase activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99828

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99828

EF-hand 1, calcium-binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99828

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016