RNA binding motif protein 8A (Q21116039)

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mammalian protein found in Homo sapiens

BOV-1
RNA-binding protein 8A
binder of OVCA1-1
ribonucleoprotein RBM8
ribonucleoprotein RBM8A
RNA-binding protein Y14
RBM8A
RNA binding motif protein 8B
binder of OVCA1
RNA-binding motif protein 8A

Language	Label	Description	Also known as
English	RNA binding motif protein 8A	mammalian protein found in Homo sapiens	BOV-1 RNA-binding protein 8A binder of OVCA1-1 ribonucleoprotein RBM8 ribonucleoprotein RBM8A RNA-binding protein Y14 RBM8A RNA binding motif protein 8B binder of OVCA1 RNA-binding motif protein 8A

Statements

1 reference

13 November 2019

UniProt protein ID

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5S9

RNA-binding motif protein 8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5S9

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5S9

P-P-bond-hydrolysis-driven transporter

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

RBM8, RNA recognition motif, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA recognition motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method or standard

20 references

8 April 2019

Disassembly of exon junction complexes by PYM

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

The protein interaction landscape of the human CMGC kinase group

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

A novel mode of RBD-protein recognition in the Y14–Mago complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

eIF4A3 is a novel component of the exon junction complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Structure of the Y14-Magoh core of the exon junction complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Disassembly of exon junction complexes by PYM

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

MAGOH interacts with a novel RNA-binding protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

nucleic acid binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

4 references

17 October 2017

Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

3 references

8 April 2019

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

4 references

8 April 2019

Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

catalytic step 2 spliceosome

determination method or standard

1 reference

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

exon-exon junction complex

determination method or standard

3 references

17 October 2017

Disassembly of exon junction complexes by PYM

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

neuronal cell body

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

spliceosomal complex

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

5 references

1 January 2018

Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

1 January 2018

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

3 references

8 April 2019

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

exon-exon junction complex

determination method or standard

4 references

8 April 2019

Disassembly of exon junction complexes by PYM

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

6 references

8 April 2019

Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Structure of a human catalytic step I spliceosome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

U2-type catalytic step 1 spliceosome

determination method or standard

1 reference

8 April 2019

Structure of a human catalytic step I spliceosome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

biological process

termination of RNA polymerase II transcription

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

mRNA processing

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

regulation of alternative mRNA splicing, via spliceosome

determination method or standard

1 reference

17 October 2017

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

mRNA export from nucleus

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

mRNA 3'-end processing

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

regulation of translation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

RNA export from nucleus

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

determination method or standard

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5S9&geneProductId=UniProtKB:Q9Y5S9

determination method or standard

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

regulation of alternative mRNA splicing, via spliceosome

determination method or standard

mRNA splicing, via spliceosome

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Structure of a human catalytic step I spliceosome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5S9

determination method or standard

RNA recognition motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5S9

RBM8, RNA recognition motif

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5S9

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000358313

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358313

ENSP00000463058

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463058

ENSP00000488265

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000488265

ENSP00000487764

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487764

ENSP00000488887

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000488887

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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