Flotillin 1 (Q21116126)

Flotillin family

1 reference

Flotillin, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Band 7 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

7 references

1 January 2018

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Analysis of close associations of uropod-associated proteins in human T-cells using the proximity ligation assay

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Role of dynamin and clathrin in the cellular trafficking of flotillins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Arginase-flotillin interaction brings arginase to red blood cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

protein heterodimerization activity

1 reference

1 January 2018

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

ionotropic glutamate receptor binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

integral component of membrane

cell component

TAS

1 reference

26 September 2017

Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

TAS

membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

3 references

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

cell-cell contact zone

1 reference

1 January 2018

Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

focal adhesion

1 reference

26 September 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

plasma membrane raft

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

melanosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 reference

1 January 2018

plasma membrane

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

26 September 2017

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

centriolar satellite

1 reference

1 January 2018

Novel interaction partners of Bardet-Biedl syndrome proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

microtubule organizing center

1 reference

1 January 2018

Novel interaction partners of Bardet-Biedl syndrome proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

lysosomal membrane

1 reference

26 September 2017

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

flotillin complex

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin microdomains stabilize cadherins at cell-cell junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

uropod

1 reference

1 January 2018

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

basolateral plasma membrane

1 reference

1 January 2018

Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

early endosome

1 reference

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

apical plasma membrane

1 reference

1 January 2018

Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

cortical actin cytoskeleton

1 reference

1 January 2018

Flotillin microdomains stabilize cadherins at cell-cell junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

caveola

Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

membrane raft

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

4 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

COP9 signalosome

1 reference

1 January 2018

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

sarcolemma

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

extracellular exosome

4 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955

cytoplasmic vesicle

1 reference

1 January 2018

Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

lamellipodium

1 reference

1 January 2018

Flotillin microdomains stabilize cadherins at cell-cell junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

cell-cell junction

1 reference

1 January 2018

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

lysosomal membrane

1 reference

1 January 2018

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

plasma membrane

Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

TAS

1 January 2018

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

focal adhesion

1 reference

1 January 2018

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

external side of plasma membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

3 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

synapse

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

presynaptic active zone

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

extracellular exosome

3 references

1 January 2018

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

dopaminergic synapse

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

EXP

presynapse

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

glutamatergic synapse

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

GABA-ergic synapse

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of cell adhesion molecule production

biological process

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of protein phosphorylation

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

regulation of toll-like receptor 4 signaling pathway

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of heterotypic cell-cell adhesion

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of toll-like receptor 3 signaling pathway

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

axonogenesis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of cytokine production

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

extracellular matrix disassembly

1 reference

1 January 2018

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

response to endoplasmic reticulum stress

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

protein localization to membrane raft

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

membrane raft assembly

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

cellular response to exogenous dsRNA

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

regulation of Rho protein signal transduction

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

protein homooligomerization

1 reference

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

dsRNA transport

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

plasma membrane raft assembly

1 reference

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of interferon-beta production

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

protein stabilization

1 reference

1 January 2018

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

protein localization to plasma membrane

Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin microdomains stabilize cadherins at cell-cell junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

regulation of neurotransmitter uptake

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 January 2018

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

positive regulation of NF-kappaB transcription factor activity

EXP

1 reference

1 January 2018

Downregulation of miR-138 sustains NF-κB activation and promotes lipid raft formation in esophageal squamous cell carcinoma.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955

1 reference

Flotillin, C-terminal domain

1 reference

Transporter Classification Database ID

Identifiers

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

13 November 2019

1 reference

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1 reference

8.A.21.3.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database