Ubiquilin 4 (Q21116430)

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mammalian protein found in Homo sapiens

connexin43-interacting protein of 75 kDa
CIP75
UBQLN4
ataxin-1 interacting ubiquitin-like protein
ataxin-1 ubiquitin-like interacting protein
ubiquilin-4
ataxin-1 ubiquitin-like-interacting protein A1U
A1Up

Language	Label	Description	Also known as
English	Ubiquilin 4	mammalian protein found in Homo sapiens	connexin43-interacting protein of 75 kDa CIP75 UBQLN4 ataxin-1 interacting ubiquitin-like protein ataxin-1 ubiquitin-like interacting protein ubiquilin-4 ataxin-1 ubiquitin-like-interacting protein A1U A1Up

Statements

1 reference

13 November 2019

UniProt protein ID

UBA-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NRR5

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NRR5

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Ubiquitin-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Heat shock chaperonin-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

polyubiquitin modification-dependent protein binding

determination method or standard

1 reference

7 November 2018

The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NRR5&geneProductId=UniProtKB:Q9NRR5

determination method or standard

protein binding

determination method or standard

9 references

9 May 2019

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Herp enhances ER-associated protein degradation by recruiting ubiquilins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Ubiquitin-independent Proteasomal Degradation of Endoplasmic Reticulum-localized Connexin43 Mediated by CIP75

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

identical protein binding

determination method or standard

3 references

9 May 2019

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

polyubiquitin modification-dependent protein binding

determination method or standard

3 references

9 May 2019

The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

determination method or standard

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

perinuclear region of cytoplasm

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

nuclear proteasome complex

determination method or standard

1 reference

9 May 2019

The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

cytosolic proteasome complex

determination method or standard

1 reference

7 November 2018

The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NRR5&geneProductId=UniProtKB:Q9NRR5

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

determination method or standard

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

determination method or standard

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

site of DNA damage

determination method or standard

1 reference

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

biological process

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

negative regulation of autophagosome maturation

determination method or standard

1 reference

9 May 2019

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method or standard

1 reference

1 January 2018

The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

ubiquitin-dependent protein catabolic process

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method or standard

negative regulation of double-strand break repair via homologous recombination

determination method or standard

1 reference

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NRR5

determination method or standard

Ubiquitin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NRR5

Heat shock chaperonin-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NRR5

Ubiquitin-associated domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NRR5

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000357292

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000357292

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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