CCAAT enhancer binding protein beta (Q21116787)

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mammalian protein found in Homo sapiens

Liver-enriched inhibitory protein
interleukin 6-dependent DNA-binding protein
nuclear factor of interleukin 6
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
nuclear factor NF-IL6
CCAAT/enhancer-binding protein beta
LAP
Liver activator protein
TCF-5
LIP
transcription factor 5
transcription factor C/EBP beta

Language	Label	Description	Also known as
English	CCAAT enhancer binding protein beta	mammalian protein found in Homo sapiens	Liver-enriched inhibitory protein interleukin 6-dependent DNA-binding protein nuclear factor of interleukin 6 CEBPB CCAAT/enhancer binding protein (C/EBP), beta nuclear factor NF-IL6 CCAAT/enhancer-binding protein beta LAP Liver activator protein TCF-5 LIP transcription factor 5 transcription factor C/EBP beta

Statements

1 reference

13 November 2019

UniProt protein ID

CCAAT/enhancer-binding protein, chordates

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17676

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

3 references

8 April 2019

Divergent hTAFII31-binding motifs hidden in activation domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

RNA polymerase II transcription regulatory region sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

transcription factor binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

histone deacetylase binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

chromatin binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

protein binding

determination method or standard

7 references

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

The Papillomavirus E2 protein binds to and synergizes with C/EBP factors involved in keratinocyte differentiation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

MUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Physical interaction and mutual transrepression between CCAAT/enhancer-binding protein beta and the p53 tumor suppressor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

histone acetyltransferase binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

ubiquitin-like protein ligase binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

RNA polymerase II core promoter sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

4 references

5 June 2018

The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

4 references

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

5 June 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

glucocorticoid receptor binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

5 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

determination method or standard

4 references

8 April 2019

Divergent hTAFII31-binding motifs hidden in activation domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

condensed chromosome, centromeric region

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

RNA polymerase II transcription regulator complex

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

biological process

negative regulation of neuron apoptotic process

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

mammary gland epithelial cell proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

cell differentiation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

determination method or standard

1 reference

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

cellular response to organic cyclic compound

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

embryonic placenta development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

response to endoplasmic reticulum stress

determination method or standard

1 reference

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

mammary gland epithelial cell differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

positive regulation of transcription, DNA-templated

determination method or standard

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

positive regulation of osteoblast differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

response to lipopolysaccharide

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

acute-phase response

determination method or standard

1 reference

8 April 2019

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

immune response

determination method or standard

1 reference

8 April 2019

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

neuron differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

cellular response to interleukin-1

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

brown fat cell differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

cellular response to amino acid stimulus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

liver development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

inflammatory response

determination method or standard

1 reference

8 April 2019

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

negative regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

cellular response to lipopolysaccharide

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

fat cell differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Divergent hTAFII31-binding motifs hidden in activation domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

granuloma formation

determination method or standard

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

T-helper 1 cell activation

determination method or standard

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17676&geneProductId=UniProtKB:P17676

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

regulation of odontoblast differentiation

determination method or standard

positive regulation of transcription, DNA-templated

determination method or standard

3 references

8 April 2019

Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

8 April 2019

Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

positive regulation of biomineral tissue development

determination method or standard

positive regulation of sodium-dependent phosphate transport

determination method or standard

positive regulation of inflammatory response

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

regulation of dendritic cell differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17676

determination method or standard

Basic-leucine zipper domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17676

Identifiers

MeSH descriptor ID

subject named as

CCAAT-Enhancer-Binding Protein-beta

0 references

D12.776.260.108.124.750

0 references

D12.776.660.167.750

0 references

D12.776.930.127.124.750

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000305422

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000305422

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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