DNA damage inducible transcript 3 (Q21116814)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35638

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Regulation of aldehyde reductase expression by STAF and CHOP

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

cAMP response element binding protein binding

1 reference

8 April 2019

The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

transcription corepressor activity

1 reference

8 April 2019

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

DNA-binding transcription factor activity

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

DNA-binding transcription activator activity, RNA polymerase II-specific

2 references

27 March 2018

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

8 April 2019

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

transcription cis-regulatory region binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

27 March 2018

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

leucine zipper domain binding

protein binding

11 references

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Network organization of the human autophagy system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

protein heterodimerization activity

Roles of CHOP/GADD153 in endoplasmic reticulum stress

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

NAS

8 April 2019

Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

3 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

NAS

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

RNA polymerase II cis-regulatory region sequence-specific DNA binding

ISA

DNA-binding transcription activator activity, RNA polymerase II-specific

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

2 references

1 January 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

cell component

cytosol

1 reference

8 April 2019

Roles of CHOP/GADD153 in endoplasmic reticulum stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

late endosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

CHOP-C/EBP complex

Roles of CHOP/GADD153 in endoplasmic reticulum stress

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

1 reference

8 April 2019

protein-DNA complex

1 reference

8 April 2019

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

CHOP-ATF4 complex

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

2 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

CHOP-ATF3 complex

1 reference

27 March 2018

Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

6 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

CHOP-C/EBP complex

Roles of CHOP/GADD153 in endoplasmic reticulum stress

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

CHOP-ATF4 complex

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

CHOP-ATF3 complex

release of sequestered calcium ion into cytosol

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of protein kinase B signaling

1 reference

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of fat cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of myoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

regulation of transcription, DNA-templated

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

1 reference

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

ISS

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

mRNA transcription by RNA polymerase II

1 reference

8 April 2019

Regulation of aldehyde reductase expression by STAF and CHOP

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

positive regulation of neuron death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of transcription by RNA polymerase II

The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

1 reference

8 April 2019

cell redox homeostasis

1 reference

8 April 2019

Regulation of aldehyde reductase expression by STAF and CHOP

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

response to endoplasmic reticulum stress

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

PERK-mediated unfolded protein response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

3 references

8 April 2019

8 April 2019

The endoplasmic reticulum stress response in aging and age-related diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Roles of CHOP/GADD153 in endoplasmic reticulum stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

ER overload response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

cellular response to DNA damage stimulus

1 reference

8 April 2019

Isolation, characterization and chromosomal localization of the human GADD153 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

1 reference

27 March 2018

positive regulation of transcription, DNA-templated

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

response to unfolded protein

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Roles of CHOP/GADD153 in endoplasmic reticulum stress

6 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

The endoplasmic reticulum stress response in aging and age-related diseases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

27 March 2018

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638

negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

positive regulation of interleukin-8 production

1 reference

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

response to starvation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

1 reference

8 April 2019

regulation of DNA-templated transcription in response to stress

1 reference

8 April 2019

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

3 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

blood vessel maturation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of CREB transcription factor activity

IGI

endoplasmic reticulum unfolded protein response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

establishment of protein localization to mitochondrion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

intrinsic apoptotic signaling pathway in response to nitrosative stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

negative regulation of DNA-binding transcription factor activity

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

protein complex oligomerization

1 reference

8 April 2019

Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

The endoplasmic reticulum stress response in aging and age-related diseases

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Roles of CHOP/GADD153 in endoplasmic reticulum stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

regulation of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

1 reference

8 April 2019

positive regulation of neuron apoptotic process

ISS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

8 April 2019

CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638

Basic-leucine zipper domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35638

Identifiers

MeSH descriptor ID

D051742

subject named as

Transcription Factor CHOP

0 references

MeSH tree code

D12.776.260.108.124.875

0 references

D12.776.660.167.875

0 references

D12.776.930.127.124.875

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023