Purinergic receptor P2X 1 (Q21118919)

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mammalian protein found in Homo sapiens

• ATP receptor
• P2X receptor, subunit 1
• P2X purinoceptor 1
• P2X1 receptor
• purinergic receptor P2X1
• Purinergic receptor
• purinergic receptor P2X, ligand gated ion channel, 1
• P2RX1

edit

Language	Label	Description	Also known as
English	Purinergic receptor P2X 1	mammalian protein found in Homo sapiens	ATP receptor P2X receptor, subunit 1 P2X purinoceptor 1 P2X1 receptor purinergic receptor P2X1 Purinergic receptor purinergic receptor P2X, ligand gated ion channel, 1 P2RX1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51575

part of

P2X purinoreceptor extracellular domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51575

P2X1 purinoceptor

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51575

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51575

encoded by

P2RX1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51575

molecular function

zinc ion binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

purinergic nucleotide receptor activity

determination method or standard

IDA

IEA

3 references

retrieved

16 July 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51575&geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

16 July 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51575&geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

16 July 2018

stated in

Characterization and chromosomal localization of a human P2X receptor from the urinary bladder

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51575&geneProductId=UniProtKB:P51575

determination method or standard

IDA

ion channel activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

cation channel activity

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

Characterization and chromosomal localization of a human P2X receptor from the urinary bladder

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IDA

ATP binding

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

extracellularly ATP-gated cation channel activity

determination method or standard

IBA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

purinergic nucleotide receptor activity

determination method or standard

IBA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

Characterization and chromosomal localization of a human P2X receptor from the urinary bladder

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

ATP-gated ion channel activity

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

cell component

integral component of membrane

determination method or standard

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P51575

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51575&geneProductId=UniProtKB:P51575

determination method or standard

IEA

postsynaptic membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

membrane

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51575

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

plasma membrane

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

integral component of nuclear inner membrane

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

integral component of plasma membrane

determination method or standard

IEA

TAS

2 references

retrieved

8 April 2019

stated in

P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

membrane raft

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

neuron projection

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

secretory granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

specific granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

external side of plasma membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

protein-containing complex

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

glutamatergic synapse

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

integral component of postsynaptic membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

integral component of presynaptic active zone membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

integral component of membrane

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51575

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

biological process

response to ATP

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of calcium ion transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

synaptic transmission, glutamatergic

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

protein heterooligomerization

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of smooth muscle contraction

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

vasoconstriction

determination method or standard

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51575&geneProductId=UniProtKB:P51575

determination method or standard

IEA

ceramide biosynthetic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

serotonin secretion by platelet

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

blood coagulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

ion transport

determination method or standard

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51575

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

retrieved

8 April 2019

stated in

Characterization and chromosomal localization of a human P2X receptor from the urinary bladder

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IDA

response to organic substance

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

cation transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

platelet activation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of blood pressure

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of vasoconstriction

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

positive regulation of ion transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

insemination

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

protein homooligomerization

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of vascular associated smooth muscle contraction

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

neuronal action potential

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

signal transduction

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

apoptotic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51575

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

purinergic nucleotide receptor signaling pathway

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

neutrophil degranulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

TAS

excitatory postsynaptic potential

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of presynaptic cytosolic calcium ion concentration

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

regulation of synaptic vesicle exocytosis

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IEA

cation transport

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

ion transmembrane transport

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51575

determination method or standard

IBA

physically interacts with

adenosine triphosphate

has use

agonist

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1713

language of work or name

English

retrieved

17 August 2016

Identifiers

RefSeq protein ID

NP_002549

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

XP_006721592

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

XP_011522198

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

XP_011522199

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

XP_011522200

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

XP_011522201

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

XP_011522202

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5023

UniProt protein ID

P51575

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51575

Ensembl protein ID

ENSP00000225538

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000225538

ENSP00000460449

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000460449

Transporter Classification Database ID

1.A.7.1.1

1 reference

based on heuristic

TCDB BLAST

 

Sitelinks

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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