Protein phosphatase 2 phosphatase activator (Q21112625)

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mammalian protein found in Homo sapiens

serine/threonine-protein phosphatase 2A activator
PP2A phosphatase activator
Serine/threonine-protein phosphatase 2A regulatory subunit 4
PP2A, subunit B', PR53 isoform
serine/threonine-protein phosphatase 2A regulatory subunit B'
PP2A subunit B' isoform PR53
protein phosphatase 2A, regulatory subunit B' (PR 53)
protein phosphatase 2A activator, regulatory subunit 4
phosphotyrosyl phosphatase activator
PTPA
protein phosphatase 2 regulatory subunit 4
protein phosphatase 2A regulatory subunit 4

Language	Label	Description	Also known as
English	Protein phosphatase 2 phosphatase activator	mammalian protein found in Homo sapiens	serine/threonine-protein phosphatase 2A activator PP2A phosphatase activator Serine/threonine-protein phosphatase 2A regulatory subunit 4 PP2A, subunit B', PR53 isoform serine/threonine-protein phosphatase 2A regulatory subunit B' PP2A subunit B' isoform PR53 protein phosphatase 2A, regulatory subunit B' (PR 53) protein phosphatase 2A activator, regulatory subunit 4 phosphotyrosyl phosphatase activator PTPA protein phosphatase 2 regulatory subunit 4 protein phosphatase 2A regulatory subunit 4

Statements

1 reference

13 November 2019

UniProt protein ID

Phosphotyrosyl phosphatase activator, PTPA

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15257

PTPA superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15257

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein tyrosine phosphatase activator activity

determination method or standard

protein homodimerization activity

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

isomerase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

ATPase activity

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein heterodimerization activity

determination method or standard

1 reference

8 April 2019

A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein phosphatase 2A binding

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

phosphatase activator activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

signaling receptor binding

determination method or standard

1 reference

8 April 2019

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein phosphatase regulator activity

determination method or standard

protein tyrosine phosphatase activator activity

determination method or standard

3 references

8 April 2019

Molecular cloning, expression, and characterization of PTPA, a protein that activates the tyrosyl phosphatase activity of protein phosphatase 2A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

calcium channel complex

determination method or standard

1 reference

8 April 2019

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein phosphatase type 2A complex

determination method or standard

1 reference

26 September 2017

A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15257&geneProductId=UniProtKB:Q15257

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

extracellular exosome

determination method or standard

protein phosphatase type 2A complex

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

8 April 2019

Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

8 April 2019

Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

extracellular exosome

determination method or standard

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

biological process

negative regulation of protein dephosphorylation

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

positive regulation of protein dephosphorylation

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

regulation of phosphoprotein phosphatase activity

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

positive regulation of phosphoprotein phosphatase activity

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

positive regulation of apoptotic process

determination method or standard

1 reference

8 April 2019

Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

negative regulation of phosphoprotein phosphatase activity

determination method or standard

1 reference

8 April 2019

Structure and mechanism of the phosphotyrosyl phosphatase activator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

protein peptidyl-prolyl isomerization

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

mitotic spindle organization

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15257

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000337448

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000337448

ENSP00000347109

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000347109

ENSP00000349726

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000349726

ENSP00000351885

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000351885

ENSP00000377036

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377036

ENSP00000335200

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000335200

ENSP00000337412

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000337412

ENSP00000387726

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000387726

ENSP00000389312

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000389312

ENSP00000393092

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393092

ENSP00000393196

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393196

ENSP00000393796

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393796

ENSP00000394001

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394001

ENSP00000394338

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394338

ENSP00000395499

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395499

ENSP00000396660

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396660

ENSP00000399069

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000399069

ENSP00000400314

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400314

ENSP00000403542

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403542

ENSP00000405100

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405100

ENSP00000406997

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000406997

ENSP00000408316

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408316

ENSP00000408726

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408726

ENSP00000411604

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411604

ENSP00000416522

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416522

ENSP00000416661

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416661

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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