Eukaryotic translation initiation factor 3 subunit E (Q21113036)

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mammalian protein found in Homo sapiens
  • eukaryotic translation initiation factor 3 subunit E
  • eIF-3 p48
  • mammary tumor-associated protein INT6
  • murine mammary tumor integration site 6 (oncogene homolog)
  • eukaryotic translation initiation factor 3, subunit 6 (48kD)
  • eukaryotic translation initiation factor 3, subunit 6 48kDa
  • eukaryotic translation initiation factor 3 subunit E isoform 2 transcript
  • eukaryotic translation initiation factor 3 subunit 6
  • EIF3E
  • viral integration site protein INT-6 homolog
edit
Language Label Description Also known as
English
Eukaryotic translation initiation factor 3 subunit E
mammalian protein found in Homo sapiens
  • eukaryotic translation initiation factor 3 subunit E
  • eIF-3 p48
  • mammary tumor-associated protein INT6
  • murine mammary tumor integration site 6 (oncogene homolog)
  • eukaryotic translation initiation factor 3, subunit 6 (48kD)
  • eukaryotic translation initiation factor 3, subunit 6 48kDa
  • eukaryotic translation initiation factor 3 subunit E isoform 2 transcript
  • eukaryotic translation initiation factor 3 subunit 6
  • EIF3E
  • viral integration site protein INT-6 homolog

Statements

molecular function
translation initiation factor activity
determination method or standard
IC
IDA
IEA
8 references
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
Reconstitution reveals the functional core of mammalian eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
17 October 2017
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
17 October 2017
stated in
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IC
protein binding
determination method or standard
IPI
14 references
retrieved
1 January 2018
stated in
Human INT6/eIF3e is required for nonsense-mediated mRNA decay
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Human DDX3 functions in translation and interacts with the translation initiation factor eIF3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Mammalian tumor suppressor Int6 specifically targets hypoxia inducible factor 2 alpha for degradation by hypoxia- and pVHL-independent regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Global landscape of HIV-human protein complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Architecture of human translation initiation factor 3.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
retrieved
1 January 2018
stated in
Int6 regulates both proteasomal degradation and translation initiation and is critical for proper formation of acini by human mammary epithelium
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IPI
translation initiation factor activity
determination method or standard
IBA
IC
IDA
IEA
9 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
Reconstitution reveals the functional core of mammalian eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
1 January 2018
stated in
The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
1 January 2018
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IBA
cell component
eukaryotic translation initiation factor 3 complex
determination method or standard
NAS
IDA
IEA
8 references
retrieved
17 October 2017
stated in
Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
NAS
retrieved
17 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
Reconstitution reveals the functional core of mammalian eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
eukaryotic translation initiation factor 3 complex
determination method or standard
IBA
IDA
IEA
NAS
9 references
retrieved
1 January 2018
stated in
Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
NAS
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
Reconstitution reveals the functional core of mammalian eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IBA
biological process
translational initiation
determination method or standard
IC
IDA
TAS
IEA
6 references
retrieved
17 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
TAS
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
17 October 2017
stated in
Reconstitution reveals the functional core of mammalian eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
17 October 2017
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
17 October 2017
stated in
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60228&geneProductId=UniProtKB:P60228
determination method or standard
IC
translational initiation
determination method or standard
IBA
IC
IDA
IEA
TAS
7 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
TAS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IEA
retrieved
1 January 2018
stated in
Reconstitution reveals the functional core of mammalian eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IDA
retrieved
1 January 2018
stated in
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
1 January 2018
stated in
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
GOA
curator
UniProt
UniProt protein ID
P60228
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IC
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60228
determination method or standard
IBA

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21113036&oldid=2022952137"