S100 calcium binding protein A7 (Q21124358)

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mammalian protein found in Homo sapiens

• protein S100-A7
• S100 calcium-binding protein A7
• Psoriasin
• S100A7
• psoriasin 1

edit

Language	Label	Description	Also known as
English	S100 calcium binding protein A7	mammalian protein found in Homo sapiens	protein S100-A7 S100 calcium-binding protein A7 Psoriasin S100A7 psoriasin 1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31151

part of

protein S100-A7

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

EF-hand domain pair

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

S-100, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/CaBP-9k-type, calcium binding, subdomain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EF-Hand 1, calcium-binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/Calbindin-D9k, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31151

encoded by

S100A7

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31151

molecular function

calcium ion binding

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IEA

retrieved

8 April 2019

stated in

Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

zinc ion binding

determination method or standard

IC

NAS

2 references

retrieved

8 April 2019

stated in

Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

NAS

retrieved

8 April 2019

stated in

Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IC

metal ion binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IEA

protein binding

determination method or standard

IPI

3 references

retrieved

8 April 2019

stated in

RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IPI

retrieved

8 April 2019

stated in

S100A7 (psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IPI

retrieved

8 April 2019

stated in

RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IPI

RAGE receptor binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IPI

transition metal ion binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IEA

cell component

cytoplasm

determination method or standard

IDA

IEA

TAS

3 references

retrieved

8 April 2019

stated in

Psoriasin (S100A7)

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IEA

retrieved

8 April 2019

stated in

Psoriasin (S100A7) expression and invasive breast cancer

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

cytosol

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

S100A7 (psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

focal adhesion

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

S100A7 (psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

NAS

extracellular region

determination method or standard

IDA

IEA

TAS

5 references

retrieved

8 April 2019

stated in

Psoriasin (S100A7)

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IEA

retrieved

8 April 2019

stated in

Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

retrieved

8 April 2019

stated in

Psoriasin expression in mammary epithelial cells in vitro and in vivo

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

endoplasmic reticulum

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

S100A7 (psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

nucleus

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Psoriasin (S100A7) expression and invasive breast cancer

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

azurophil granule lumen

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

extracellular space

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

extracellular matrix

determination method or standard

IDA

1 reference

retrieved

27 March 2018

stated in

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31151&geneProductId=UniProtKB:P31151

determination method or standard

IDA

collagen-containing extracellular matrix

determination method or standard

HDA

1 reference

retrieved

8 April 2019

stated in

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

HDA

biological process

response to reactive oxygen species

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Psoriasin (S100A7) and calgranulin-B (S100A9) induction is dependent on reactive oxygen species and is downregulated by Bcl-2 and antioxidants

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

positive regulation of monocyte chemotaxis

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

keratinocyte differentiation

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

Expression patterns of S100A7 (psoriasin) and S100A9 (calgranulin-B) in keratinocyte differentiation

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

NAS

positive regulation of granulocyte chemotaxis

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

sequestering of metal ion

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

response to lipopolysaccharide

determination method or standard

IEP

1 reference

retrieved

8 April 2019

stated in

S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IEP

positive regulation of T cell chemotaxis

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

angiogenesis

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

A putative role for psoriasin in breast tumor progression

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

NAS

positive regulation of ERK1 and ERK2 cascade

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IDA

epidermis development

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

innate immune response

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

NAS

antimicrobial humoral response

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

neutrophil degranulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

TAS

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

GOA

curator

UniProt

UniProt protein ID

P31151

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31151

determination method or standard

IMP

has part(s)

EF-hand domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

S100/CaBP-9k-type, calcium binding, subdomain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

S100/Calbindin-D9k, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

EF-hand 1, calcium-binding site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

S-100

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31151

Identifiers

NL CR AUT ID

ph883444

subject named as

psoriasin

0 references

RefSeq protein ID

NP_002954

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

6278

UniProt protein ID

P31151

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31151

Ensembl protein ID

ENSP00000357711

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000357711

ENSP00000357712

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000357712

Freebase ID

/m/02kgjjw

0 references

Microsoft Academic ID

205563353

0 references

PDB structure ID

1PSR

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

2PSR

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

2WND

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

2WOR

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

2WOS

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

3PSR

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

4AQJ

1 reference

stated in

UniProt

UniProt protein ID

P31151

retrieved

20 March 2016

language of work or name

English

 

Sitelinks

Wikipedia(4 entries)

edit

• cywiki S100A7
• dewiki Psoriasin
• enwiki S100A7
• ukwiki S100A7

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21124358&oldid=2023003134"